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st6galnac1.2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2 [ Danio rerio (zebrafish) ]

Gene ID: 799868, updated on 25-Apr-2024

Summary

Official Symbol
st6galnac1.2provided by ZNC
Official Full Name
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-041014-161
See related
Ensembl:ENSDARG00000043816 AllianceGenome:ZFIN:ZDB-GENE-041014-161
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
siat3; si:ch211-51n14.2
Summary
Predicted to enable sialyltransferase activity. Predicted to act upstream of or within protein glycosylation. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Is expressed in brain; gill; integument; liver; and pleuroperitoneal region. Orthologous to human ST6GALNAC1 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See st6galnac1.2 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (20691310..20699183)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (20569436..20577309)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 1 Neighboring gene gastric inhibitory polypeptide Neighboring gene CASK interacting protein 2 Neighboring gene NME/NM23 nucleoside diphosphate kinase 2a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables sialyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in oligosaccharide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1.2
Names
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1.2
alpha-2,6-sialyltransferase ST6GalNAc I
st6galnac1-r2
NP_001076403.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082934.1NP_001076403.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1.2

    See identical proteins and their annotated locations for NP_001076403.1

    Status: PROVISIONAL

    Source sequence(s)
    CR385044
    UniProtKB/TrEMBL
    A8WFW6, Q5P991
    Related
    ENSDARP00000064334.4, ENSDART00000064335.6
    Conserved Domains (1) summary
    pfam00777
    Location:139423
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    20691310..20699183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)