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carB carbamoyl-phosphate synthase large subunit [ Ferroglobus placidus DSM 10642 ]

Gene ID: 8777815, updated on 15-Apr-2023

Summary

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Gene symbol
carB
Gene description
carbamoyl-phosphate synthase large subunit
Locus tag
FERP_RS01620
Gene type
protein coding
Organism
Ferroglobus placidus DSM 10642 (strain: DSM 10642, culture-collection: DSM:10642, type-material: type strain of Ferroglobus placidus)
Lineage
Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae; Ferroglobus
Old locus tag
Ferp_0317
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Genomic context

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Sequence:
NC_013849.1 (275254..278499, complement)

NC_013849.1Genomic Context describing neighboring genes Neighboring gene MFS transporter Neighboring gene hypothetical protein Neighboring gene nickel pincer cofactor biosynthesis protein LarB Neighboring gene glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit Neighboring gene AIR carboxylase family protein Neighboring gene phosphoribosylaminoimidazolesuccinocarboxamide synthase Neighboring gene winged helix-turn-helix domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_013849.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Selective inactivation of the glutamine binding site of Escherichia coli carbamyl phosphate synthetase by 2-amino-4-oxo-5-chloropentanoic acid. Khedouri E, et al. Biochemistry, 1966 Nov. PMID 5339592
  2. Reversible dissociation of the monomer of glutamine-dependent carbamyl phosphate synthetase into catalytically active heavy and light subunits. Trotta PP, et al. J Biol Chem, 1974 Jan 25. PMID 4358555
  3. Complete genome sequence of Ferroglobus placidus AEDII12DO. Anderson I, et al. Stand Genomic Sci, 2011 Oct 15. PMID 22180810, Free PMC Article
  4. Inactivation of the amidotransferase activity of carbamoyl phosphate synthetase by the antibiotic acivicin. Miles BW, et al. J Biol Chem, 2002 Feb 8. PMID 11729189
  5. Long-range allosteric transitions in carbamoyl phosphate synthetase. Thoden JB, et al. Protein Sci, 2004 Sep. PMID 15322282, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

General protein information

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Preferred Names
carbamoyl-phosphate synthase large subunit
WP_012964844.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_013849.1 Reference assembly

    Range
    275254..278499 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_012964844.1 carbamoyl-phosphate synthase large subunit [Ferroglobus placidus]

    See identical proteins and their annotated locations for WP_012964844.1

    UniProtKB/TrEMBL
    D3S2G7
    Conserved Domains (5) summary
    PRK05294
    Location:1 → 1072
    carB; carbamoyl phosphate synthase large subunit; Reviewed
    cd01424
    Location:944 → 1053
    MGS_CPS_II; Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways ...
    pfam02786
    Location:128 → 333
    CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain
    pfam02787
    Location:424 → 549
    CPSase_L_D3; Carbamoyl-phosphate synthetase large chain, oligomerization domain
    cl17255
    Location:675 → 875
    ATP-grasp_4; ATP-grasp domain
Nucleotide Protein
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