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scpB methylmalonyl-CoA decarboxylase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947408, updated on 30-May-2019

Summary

Gene symbol
scpB
Gene description
methylmalonyl-CoA decarboxylase
Primary source
EcoGene:EG12972
Locus tag
b2919
See related
ASAP:ABE-0009581; ECOCYC:G7516
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2915; ygfG
Summary
Part of a four gene operon encoding enzymes converting succinate to propionate. [More information is available at EcoGene: EG12972]. Methylmalonyl-CoA decarboxylase is a biotin-independent enzyme that catalyzes the decarboxylation of methylmalonyl-CoA to propionyl-CoA. [More information is available at EcoCyc: G7516].

Genomic context

Sequence:
NC_000913.3 (3063993..3064778)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator ArgP Neighboring gene methylmalonyl-CoA mutase Neighboring gene methylmalonyl-CoA mutase-interacting GTPase YgfD Neighboring gene propionyl-CoA:succinate CoA transferase Neighboring gene putative LysR-type DNA-binding transcriptional regulator YgfI Neighboring gene uncharacterized protein YggE

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
carboxy-lyase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enoyl-CoA hydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
methylmalonyl-CoA decarboxylase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
fatty acid beta-oxidation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
methylmalonyl-CoA decarboxylase
NP_417394.4

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3063993..3064778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417394.4 methylmalonyl-CoA decarboxylase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417394.4

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P52045
    Conserved Domains (1) summary
    PRK11423
    Location:1261
    PRK11423; methylmalonyl-CoA decarboxylase; Provisional
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