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    Ankrd17 ankyrin repeat domain 17 [ Mus musculus (house mouse) ]

    Gene ID: 81702, updated on 17-Jul-2021

    Summary

    Official Symbol
    Ankrd17provided by MGI
    Official Full Name
    ankyrin repeat domain 17provided by MGI
    Primary source
    MGI:MGI:1932101
    See related
    Ensembl:ENSMUSG00000055204
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gt; Foe; Gtar; Mask; AA407558; AA516750; AU040470; mKIAA0697; A930008M01; 4933425K22Rik; A130069E23Rik
    Summary
    This gene encodes a protein with ankyrin repeats, which are associated with protein-protein interactions. Studies suggest that this protein is involved in liver development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
    Expression
    Ubiquitous expression in placenta adult (RPKM 15.9), whole brain E14.5 (RPKM 11.2) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ankrd17 in Genome Data Viewer
    Location:
    5; 5 E1
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (90375025..90517133, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (90227166..90368693, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (90656191..90795211, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35936 Neighboring gene cytochrome c oxidase assembly protein 18 Neighboring gene predicted gene 9958 Neighboring gene predicted gene, 35999 Neighboring gene albumin (Alb) 5' regulatory region Neighboring gene albumin

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ankyrin repeat domain-containing protein 17
    Names
    ankyrin repeat domain containing protein FOE
    gene trap ankyrin repeat protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030886.2NP_112148.2  ankyrin repeat domain-containing protein 17 isoform a

      See identical proteins and their annotated locations for NP_112148.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC140220, AC162171
      Consensus CDS
      CCDS57354.1
      UniProtKB/Swiss-Prot
      Q99NH0
      Related
      ENSMUSP00000014421.9, ENSMUST00000014421.15
      Conserved Domains (9) summary
      TIGR02926
      Location:801877
      AhaH; ATP synthase archaeal, H subunit
      smart00248
      Location:10781106
      ANK; ankyrin repeats
      COG0666
      Location:10421268
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00105
      Location:17231785
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd00204
      Location:392516
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam03938
      Location:790889
      OmpH; Outer membrane protein (OmpH-like)
      pfam12796
      Location:301390
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:13491402
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:431460
      ANK; ANK repeat [structural motif]
    2. NM_198010.2NP_932127.2  ankyrin repeat domain-containing protein 17 isoform b

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
      Source sequence(s)
      AC140220, AC162171
      Consensus CDS
      CCDS57353.1
      UniProtKB/TrEMBL
      E9QKG6
      Related
      ENSMUSP00000080587.7, ENSMUST00000081914.13
      Conserved Domains (6) summary
      COG0666
      Location:7911017
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      cd00105
      Location:14721534
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      cd00204
      Location:392516
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam12796
      Location:301390
      Ank_2; Ankyrin repeats (3 copies)
      pfam13637
      Location:10981151
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:431460
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      90375025..90517133 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006535289.5XP_006535352.3  ankyrin repeat domain-containing protein 17 isoform X3

      Conserved Domains (7) summary
      smart00248
      Location:11171145
      ANK; ankyrin repeats
      PHA03095
      Location:11321395
      PHA03095; ankyrin-like protein; Provisional
      PHA03247
      Location:21472483
      PHA03247; large tegument protein UL36; Provisional
      cd00105
      Location:17621824
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      sd00045
      Location:722751
      ANK; ANK repeat [structural motif]
      pfam03154
      Location:19312359
      Atrophin-1; Atrophin-1 family
      pfam12796
      Location:855946
      Ank_2; Ankyrin repeats (3 copies)
    2. XM_006535287.5XP_006535350.3  ankyrin repeat domain-containing protein 17 isoform X1

      Related
      ENSMUSP00000128960.4, ENSMUST00000168058.7
      Conserved Domains (8) summary
      PHA03095
      Location:13831646
      PHA03095; ankyrin-like protein; Provisional
      PHA03247
      Location:23982734
      PHA03247; large tegument protein UL36; Provisional
      cd00105
      Location:20132075
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      sd00045
      Location:722751
      ANK; ANK repeat [structural motif]
      pfam03154
      Location:21822610
      Atrophin-1; Atrophin-1 family
      pfam12796
      Location:855946
      Ank_2; Ankyrin repeats (3 copies)
      pfam03938
      Location:10811180
      OmpH; Outer membrane protein (OmpH-like)
      cl39094
      Location:13611399
      Ank_2; Ankyrin repeats (3 copies)
    3. XM_006535288.5XP_006535351.3  ankyrin repeat domain-containing protein 17 isoform X2

      Conserved Domains (8) summary
      PHA03095
      Location:13841647
      PHA03095; ankyrin-like protein; Provisional
      PHA03247
      Location:23992735
      PHA03247; large tegument protein UL36; Provisional
      cd00105
      Location:20142076
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      sd00045
      Location:722751
      ANK; ANK repeat [structural motif]
      pfam03154
      Location:21832611
      Atrophin-1; Atrophin-1 family
      pfam12796
      Location:855946
      Ank_2; Ankyrin repeats (3 copies)
      pfam03938
      Location:10811180
      OmpH; Outer membrane protein (OmpH-like)
      cl39094
      Location:13621400
      Ank_2; Ankyrin repeats (3 copies)
    4. XM_006535290.4XP_006535353.1  ankyrin repeat domain-containing protein 17 isoform X5

      UniProtKB/TrEMBL
      A0A0G2JDZ9
      Related
      ENSMUSP00000142575.2, ENSMUST00000197021.2
      Conserved Domains (7) summary
      PHA03095
      Location:9841247
      PHA03095; ankyrin-like protein; Provisional
      PHA03247
      Location:19532335
      PHA03247; large tegument protein UL36; Provisional
      cd00105
      Location:16141676
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      sd00045
      Location:322351
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:455546
      Ank_2; Ankyrin repeats (3 copies)
      pfam03938
      Location:681780
      OmpH; Outer membrane protein (OmpH-like)
      cl39094
      Location:9621000
      Ank_2; Ankyrin repeats (3 copies)
    5. XM_030254925.1XP_030110785.1  ankyrin repeat domain-containing protein 17 isoform X7

      Conserved Domains (7) summary
      smart00248
      Location:718746
      ANK; ankyrin repeats
      PHA03095
      Location:733996
      PHA03095; ankyrin-like protein; Provisional
      PHA03247
      Location:17482084
      PHA03247; large tegument protein UL36; Provisional
      cd00105
      Location:13631425
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      sd00045
      Location:322351
      ANK; ANK repeat [structural motif]
      pfam03154
      Location:15321960
      Atrophin-1; Atrophin-1 family
      pfam12796
      Location:455546
      Ank_2; Ankyrin repeats (3 copies)
    6. XM_036165629.1XP_036021522.1  ankyrin repeat domain-containing protein 17 isoform X6

      Conserved Domains (7) summary
      PHA03095
      Location:9671230
      PHA03095; ankyrin-like protein; Provisional
      PHA03247
      Location:19362318
      PHA03247; large tegument protein UL36; Provisional
      sd00045
      Location:305334
      ANK; ANK repeat [structural motif]
      pfam03938
      Location:664763
      OmpH; Outer membrane protein (OmpH-like)
      pfam12796
      Location:438529
      Ank_2; Ankyrin repeats (3 copies)
      cd22502
      Location:15961666
      KH-I_ANKRD17; type I K homology (KH) RNA-binding domain found in ankyrin repeat domain-containing protein 17 (ANKRD17) and similar proteins
      cl39094
      Location:945983
      Ank_2; Ankyrin repeats (3 copies)
    7. XM_011249595.4XP_011247897.3  ankyrin repeat domain-containing protein 17 isoform X4

      Conserved Domains (8) summary
      smart00248
      Location:13691397
      ANK; ankyrin repeats
      PHA03095
      Location:13841647
      PHA03095; ankyrin-like protein; Provisional
      PHA03247
      Location:21422510
      PHA03247; large tegument protein UL36; Provisional
      cd00105
      Location:20142076
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      sd00045
      Location:722751
      ANK; ANK repeat [structural motif]
      pfam03154
      Location:23522606
      Atrophin-1; Atrophin-1 family
      pfam12796
      Location:855946
      Ank_2; Ankyrin repeats (3 copies)
      pfam03938
      Location:10811180
      OmpH; Outer membrane protein (OmpH-like)
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