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    CCDC152 coiled-coil domain containing 152 [ Homo sapiens (human) ]

    Gene ID: 100129792, updated on 8-Mar-2024

    Summary

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    Official Symbol
    CCDC152provided by HGNC
    Official Full Name
    coiled-coil domain containing 152provided by HGNC
    Primary source
    HGNC:HGNC:34438
    See related
    Ensembl:ENSG00000198865 AllianceGenome:HGNC:34438
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CH5400
    Expression
    Broad expression in liver (RPKM 530.0), small intestine (RPKM 440.4) and 22 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    Location:
    5p12
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (42756818..42802439)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (43009758..43055382)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (42756920..42802541)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene long intergenic non-protein coding RNA 2996 Neighboring gene NANOG hESC enhancer GRCh37_chr5:42225166-42225693 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_85146 Neighboring gene NANOG hESC enhancer GRCh37_chr5:42288621-42289193 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_85179 Neighboring gene GHR upstream promoter region module A Neighboring gene zinc finger protein 35 pseudogene Neighboring gene SERPINE1 mRNA binding protein 1 pseudogene 6 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:42508817-42509317 Neighboring gene growth hormone receptor Neighboring gene GHR downstream promoter region module B Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:42756975-42757476 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:42757477-42757976 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:42804335-42804835 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:42803834-42804334 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr5:42812153-42812718 Neighboring gene uncharacterized LOC124900970 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:42847432-42847604 Neighboring gene selenoprotein P Neighboring gene MED14-independent group 3 enhancer GRCh37_chr5:42886955-42888154 Neighboring gene peptidylprolyl isomerase A pseudogene 77

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Identification of a novel endogenous long non-coding RNA that inhibits selenoprotein P translation. Mita Y, et al. Nucleic Acids Res, 2021 Jul 9. PMID 34142161, Free PMC Article
    2. Comparative gene finding in chicken indicates that we are closing in on the set of multi-exonic widely expressed human genes. Castelo R, et al. Nucleic Acids Res, 2005. PMID 15809229, Free PMC Article
    3. Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy. Sun X, et al. Acta Pharm Sin B, 2022 Feb. PMID 35256949, Free PMC Article
    4. A reference map of the human binary protein interactome. Luck K, et al. Nature, 2020 Apr. PMID 32296183, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Identification of a novel endogenous long non-coding RNA that inhibits selenoprotein P translation.
      Title: Identification of a novel endogenous long non-coding RNA that inhibits selenoprotein P translation.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 152

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134848.2 → NP_001128320.1  coiled-coil domain-containing protein 152

      See identical proteins and their annotated locations for NP_001128320.1

      Status: VALIDATED

      Source sequence(s)
      AC008945, AK127368, BC039102, DB450032, DB515085
      Consensus CDS
      CCDS47203.1
      UniProtKB/Swiss-Prot
      B3KXI4, B4E0P7, Q4G0S7, Q5BLP6
      Related
      ENSP00000354888.5, ENST00000361970.10
      Conserved Domains (2) summary
      cl25632
      Location:54 → 182
      type_I_hlyD; type I secretion membrane fusion protein, HlyD family
      cl26128
      Location:156 → 242
      tRNA-synt_1g; tRNA synthetases class I (M)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      42756818..42802439
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047416584.1 → XP_047272540.1  coiled-coil domain-containing protein 152 isoform X1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      43009758..43055382
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054351371.1 → XP_054207346.1  coiled-coil domain-containing protein 152 isoform X2

      UniProtKB/Swiss-Prot
      B3KXI4, B4E0P7, Q4G0S7, Q5BLP6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4G0S7.3 GenPept UniProtKB/Swiss-Prot:Q4G0S7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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