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    Zfp953 zinc finger protein 953 [ Mus musculus (house mouse) ]

    Gene ID: 629016, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp953provided by MGI
    Official Full Name
    zinc finger protein 953provided by MGI
    Primary source
    MGI:MGI:3612873
    See related
    Ensembl:ENSMUSG00000098905 AllianceGenome:MGI:3612873
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    E130120F12Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Zfp953 in Genome Data Viewer
    Location:
    13 B3; 13 34.54 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (67487373..67508691, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (67339309..67360572, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA F630042J09 gene Neighboring gene STARR-seq mESC enhancer starr_34898 Neighboring gene zinc finger protein 457 Neighboring gene zinc finger protein 595 Neighboring gene STARR-positive B cell enhancer ABC_E3086 Neighboring gene STARR-positive B cell enhancer ABC_E9880 Neighboring gene predicted gene 17039 Neighboring gene zinc finger protein 456 Neighboring gene STARR-positive B cell enhancer ABC_E4075 Neighboring gene zinc finger protein 429

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression. Krebs CJ, et al. Genes Dev, 2003 Nov 1. PMID 14563677, Free PMC Article
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Potential readthrough

    Included gene: Zfp456

    Homology

    General protein information

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    Preferred Names
    zinc finger protein 953

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038651.3 → NP_001033740.1  zinc finger protein 953

      See identical proteins and their annotated locations for NP_001033740.1

      Status: PROVISIONAL

      Source sequence(s)
      AC154510
      Consensus CDS
      CCDS49301.1
      UniProtKB/TrEMBL
      Q3UPV7
      Related
      ENSMUSP00000076700.8, ENSMUST00000081582.8
      Conserved Domains (5) summary
      smart00349
      Location:5 → 63
      KRAB; krueppel associated box
      COG5048
      Location:26 → 268
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:167 → 187
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:5 → 44
      KRAB; KRAB box
      pfam13465
      Location:207 → 230
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      67487373..67508691 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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