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    lsm14aa LSM14A mRNA processing body assembly factor a [ Danio rerio (zebrafish) ]

    Gene ID: 393397, updated on 25-Apr-2024

    Summary

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    Official Symbol
    lsm14aaprovided by ZNC
    Official Full Name
    LSM14A mRNA processing body assembly factor aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1567
    See related
    Ensembl:ENSDARG00000006600 AllianceGenome:ZFIN:ZDB-GENE-040426-1567
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fam61a; lsm14a; zgc:63681; zgc:66203; zgc:77302; wu:fj52e11
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in P-body assembly and stress granule assembly. Predicted to be part of messenger ribonucleoprotein complex. Predicted to be active in P-body. Orthologous to human LSM14A (LSM14A mRNA processing body assembly factor). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See lsm14aa in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (35889072..35911091)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (35384151..35406152)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene kinesin family member 21A Neighboring gene uncharacterized LOC101885762 Neighboring gene copine VIII Neighboring gene glucose-6-phosphate isomerase a Neighboring gene hydroxysteroid (17-beta) dehydrogenase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Dynamic RNA-protein interactions underlie the zebrafish maternal-to-zygotic transition. Despic V, et al. Genome Res, 2017 Jul. PMID 28381614, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC66203

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in P-body assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in stress granule assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    LSM14A mRNA processing body assembly factor a; protein LSM14 homolog A
    Names
    LSM14 homolog A
    LSM14 homolog Aa
    LSM14A, SCD6 homolog Aa
    alpha synuclein binding protein
    alphaSNBP(B)
    family with sequence similarity 61, member A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200425.2 → NP_956719.2  LSM14A mRNA processing body assembly factor a

      See identical proteins and their annotated locations for NP_956719.2

      Status: PROVISIONAL

      Source sequence(s)
      BC065337
      UniProtKB/TrEMBL
      A0A8M1PH53, Q6P111
      Related
      ENSDARP00000009428.7, ENSDART00000023453.9
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:264 → 382
      FDF; FDF domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      35889072..35911091
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021470461.1 → XP_021326136.1  protein LSM14 homolog A isoform X1

      UniProtKB/TrEMBL
      A0A8M9PUV2
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:291 → 409
      FDF; FDF domain

    2. XM_021470462.1 → XP_021326137.1  protein LSM14 homolog A isoform X2

      UniProtKB/TrEMBL
      A0A8M9P6D7
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:261 → 379
      FDF; FDF domain

    3. XM_005163175.2 → XP_005163232.1  protein LSM14 homolog A isoform X3

      UniProtKB/TrEMBL
      A0A8M2BAB1
      Conserved Domains (2) summary
      cd01736
      Location:4 → 77
      LSm14_N; Like-Sm protein 14, N-terminal domain
      pfam09532
      Location:234 → 352
      FDF; FDF domain
    Nucleotide Protein
    Heading Accession and Version

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