acad8 acyl-CoA dehydrogenase family, member 8 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: acad8provided by ZNC
Official Full Name: acyl-CoA dehydrogenase family, member 8provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-828
See related: Ensembl:ENSDARG00000042658 AllianceGenome:ZFIN:ZDB-GENE-040426-828
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:55874
Summary: Predicted to enable acyl-CoA dehydrogenase activity and flavin adenine dinucleotide binding activity. Predicted to act upstream of or within lipid metabolic process. Orthologous to human ACAD8 (acyl-CoA dehydrogenase family member 8). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (19335646..19348163)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (19399914..19412431)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables acyl-CoA dehydrogenase activity	IEA Inferred from Electronic Annotation more info
enables flavin adenine dinucleotide binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-CH group of donors	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: isobutyryl-CoA dehydrogenase, mitochondrial

Names: acyl-Coenzyme A dehydrogenase family, member 8

NP_957449.1

EC 1.3.8.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_201155.1 → NP_957449.1 isobutyryl-CoA dehydrogenase, mitochondrial

See identical proteins and their annotated locations for NP_957449.1

Status: PROVISIONAL

Source sequence(s)

BC044203

UniProtKB/TrEMBL

A0A8M1PIW2, Q7ZYY0

Related

ENSDARP00000062568.5, ENSDART00000062569.6

Conserved Domains (2) summary

cd01162
Location:43 → 417

IBD; Isobutyryl-CoA dehydrogenase

COG1960
Location:42 → 415

CaiA; Acyl-CoA dehydrogenase related to the alkylation response protein AidB [Lipid transport and metabolism]