slc27a2a solute carrier family 27 member 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: slc27a2aprovided by ZNC
Official Full Name: solute carrier family 27 member 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050706-104
See related: Ensembl:ENSDARG00000036237 AllianceGenome:ZFIN:ZDB-GENE-050706-104
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb99g05; slc27a2; im:7139614; wu:fb99g05; zgc:112376
Summary: Predicted to enable long-chain fatty acid transporter activity and long-chain fatty acid-CoA ligase activity. Predicted to act upstream of or within bile acid biosynthetic process. Predicted to be integral component of membrane. Is expressed in yolk syncytial layer. Orthologous to human SLC27A2 (solute carrier family 27 member 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 18

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (62993..73844)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (62993..73844)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity	IEA Inferred from Electronic Annotation more info
enables acid-thiol ligase activity	IEA Inferred from Electronic Annotation more info
enables fatty acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables long-chain fatty acid transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables long-chain fatty acid-CoA ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables long-chain fatty acid-CoA ligase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables perillic acid-CoA ligase (ADP-forming) activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in long-chain fatty acid import into cell	IBA Inferred from Biological aspect of Ancestor more info
involved_in long-chain fatty acid metabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: solute carrier family 27 member 2a

Names: solute carrier family 27 (fatty acid transporter), member 2; solute carrier family 27 (fatty acid transporter), member 2a

NP_001020470.1

EC 6.2.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001025299.1 → NP_001020470.1 solute carrier family 27 member 2a

See identical proteins and their annotated locations for NP_001020470.1

Status: PROVISIONAL

Source sequence(s)

BC098625

UniProtKB/TrEMBL

Q4KMC7

Related

ENSDARP00000052637.5, ENSDART00000052638.5

Conserved Domains (2) summary

PRK08279
Location:20 → 614

PRK08279; long-chain-acyl-CoA synthetase; Validated

cl17068
Location:74 → 604

AFD_class_I; Adenylate forming domain, Class I superfamily