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    Klra4 killer cell lectin-like receptor, subfamily A, member 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 690020, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Klra4provided by RGD
    Official Full Name
    killer cell lectin-like receptor, subfamily A, member 4provided by RGD
    Primary source
    RGD:1585190
    See related
    Ensembl:ENSRNOG00000053656 AllianceGenome:RGD:1585190
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 4.6), Thymus (RPKM 3.9) and 5 other tissues See more
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    Genomic context

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    Location:
    4q42
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (165005146..165026189, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (163319139..163340140, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (163628633..163649820, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene killer cell lectin-like receptor family I member 2 Neighboring gene killer cell lectin-like receptor subfamily H, member 1 Neighboring gene killer cell lectin-like receptor, subfamily A, member 5, pseudogene 3 Neighboring gene killer cell lectin-like receptor, subfamily A, member 17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    killer cell lectin-like receptor 2; killer cell lectin-like receptor 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      165005146..165026189 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039108856.2 → XP_038964784.1  killer cell lectin-like receptor 2 isoform X5

      UniProtKB/TrEMBL
      A0A8I6GFJ6
      Related
      ENSRNOP00000087855.1
      Conserved Domains (1) summary
      pfam08391
      Location:86 → 187
      Ly49; Ly49-like protein, N-terminal region

    2. XM_006237109.5 → XP_006237171.1  killer cell lectin-like receptor 2 isoform X4

      See identical proteins and their annotated locations for XP_006237171.1

      Conserved Domains (2) summary
      cd03593
      Location:194 → 269
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      pfam08391
      Location:86 → 205
      Ly49; Ly49-like protein, N-terminal region

    3. XM_063286986.1 → XP_063143056.1  killer cell lectin-like receptor 4 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K381

    4. XM_039108855.2 → XP_038964783.1  killer cell lectin-like receptor 2 isoform X5

      UniProtKB/TrEMBL
      A0A8I6GFJ6
      Conserved Domains (1) summary
      pfam08391
      Location:86 → 187
      Ly49; Ly49-like protein, N-terminal region

    5. XM_039108857.2 → XP_038964785.1  killer cell lectin-like receptor 2 isoform X5

      UniProtKB/TrEMBL
      A0A8I6GFJ6
      Conserved Domains (1) summary
      pfam08391
      Location:86 → 187
      Ly49; Ly49-like protein, N-terminal region

    6. XM_039108859.2 → XP_038964787.1  killer cell lectin-like receptor 2 isoform X5

      UniProtKB/TrEMBL
      A0A8I6GFJ6
      Conserved Domains (1) summary
      pfam08391
      Location:86 → 187
      Ly49; Ly49-like protein, N-terminal region

    7. XM_039108854.2 → XP_038964782.1  killer cell lectin-like receptor 4 isoform X3

      Conserved Domains (2) summary
      cd03593
      Location:194 → 269
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      pfam08391
      Location:86 → 205
      Ly49; Ly49-like protein, N-terminal region

    8. XM_039108858.2 → XP_038964786.1  killer cell lectin-like receptor 2 isoform X5

      UniProtKB/TrEMBL
      A0A8I6GFJ6
      Conserved Domains (1) summary
      pfam08391
      Location:86 → 187
      Ly49; Ly49-like protein, N-terminal region

    9. XM_039108852.2 → XP_038964780.1  killer cell lectin-like receptor 4 isoform X2

      Conserved Domains (2) summary
      cd03593
      Location:194 → 285
      CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)
      pfam08391
      Location:86 → 205
      Ly49; Ly49-like protein, N-terminal region

    RNA

    1. XR_005504002.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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