psmd12 proteasome 26S subunit, non-ATPase 12 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: psmd12provided by ZNC
Official Full Name: proteasome 26S subunit, non-ATPase 12provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-617
See related: Ensembl:ENSDARG00000052377 AllianceGenome:ZFIN:ZDB-GENE-030131-617
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc34f08; wu:fb38a06; wu:fc34f08; wu:fc49f02
Summary: Acts upstream of or within brain development; cranial skeletal system development; and kidney development. Predicted to be part of nuclear proteasome complex and proteasome regulatory particle, lid subcomplex. Predicted to be active in cytoplasm. Orthologous to human PSMD12 (proteasome 26S subunit, non-ATPase 12). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	6	NC_007117.7 (21526346..21534233, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	6	NC_007117.6 (19466124..19474011, complement)

Chromosome 6 - NC_007117.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc34f08.x1 (e-PCR)
- UniSTS:188030

fc28e12.x1 (e-PCR)
- UniSTS:193418

fb38a06.x1 (e-PCR)
- UniSTS:203163

AI437121 (e-PCR)
- UniSTS:206588

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within brain development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cranial skeletal system development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within kidney development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome complex	IEA Inferred from Electronic Annotation more info
part_of proteasome regulatory particle, lid subcomplex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 26S proteasome non-ATPase regulatory subunit 12

Names: proteasome (prosome, macropain) 26S subunit, non-ATPase, 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_201578.1 → NP_963872.1 26S proteasome non-ATPase regulatory subunit 12

See identical proteins and their annotated locations for NP_963872.1

Status: PROVISIONAL

Source sequence(s)

BC042325

UniProtKB/TrEMBL

A0A8N7XJF9, B2GT23, E7FB49, Q8AW07

Related

ENSDARP00000106592.3, ENSDART00000126186.4

Conserved Domains (1) summary

COG5071
Location:14 → 456

RPN5; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]