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    si:dkey-13a21.4 si:dkey-13a21.4 [ Danio rerio (zebrafish) ]

    Gene ID: 494576, updated on 27-Mar-2024

    Summary

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    Official Symbol
    si:dkey-13a21.4provided by ZNC
    Official Full Name
    si:dkey-13a21.4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040724-163
    See related
    Ensembl:ENSDARG00000026098 AllianceGenome:ZFIN:ZDB-GENE-040724-163
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zK13A21.4; zgc:110195
    Summary
    Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in endosome to lysosome transport and phagosome-lysosome fusion. Predicted to be active in late endosome; lysosome; and phagocytic vesicle. Is expressed in pronephric duct and ventral mesoderm. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See si:dkey-13a21.4 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (25430835..25435927)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (25193235..25198311)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101882529 Neighboring gene activity-dependent neuroprotector homeobox a Neighboring gene GATA binding protein 1a Neighboring gene host cell factor C1a Neighboring gene opsin 1 (cone pigments), short-wave-sensitive 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endosome to lysosome transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phagosome-lysosome fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in late endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in phagocytic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC494576

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013478.1 → NP_001013496.1  uncharacterized protein LOC494576

      See identical proteins and their annotated locations for NP_001013496.1

      Status: PREDICTED

      Source sequence(s)
      BC091450
      UniProtKB/TrEMBL
      Q5BJK1
      Related
      ENSDARP00000105621.2, ENSDART00000126403.4
      Conserved Domains (2) summary
      smart00175
      Location:9 → 174
      RAB; Rab subfamily of small GTPases
      cd01862
      Location:9 → 178
      Rab7; Rab GTPase family 7 (Rab7)

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      25430835..25435927
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021479607.1 → XP_021335282.1  uncharacterized protein LOC494576 isoform X1

      UniProtKB/TrEMBL
      A0A0R4IQH0, A0A8M9PUW0
      Related
      ENSDARP00000137679.1, ENSDART00000164999.2
      Conserved Domains (1) summary
      cd01862
      Location:9 → 174
      Rab7; Rab GTPase family 7 (Rab7)

    2. XM_021479608.1 → XP_021335283.1  uncharacterized protein LOC494576 isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q776
      Conserved Domains (1) summary
      cd01862
      Location:9 → 173
      Rab7; Rab GTPase family 7 (Rab7)

    3. XM_021479609.1 → XP_021335284.1  uncharacterized protein LOC494576 isoform X3

      UniProtKB/TrEMBL
      A0A8M9QD29
      Conserved Domains (1) summary
      cd01862
      Location:9 → 179
      Rab7; Rab GTPase family 7 (Rab7)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394822.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      56916..61982
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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