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    Zbtb44 zinc finger and BTB domain containing 44 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363035, updated on 2-May-2024

    Summary

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    Official Symbol
    Zbtb44provided by RGD
    Official Full Name
    zinc finger and BTB domain containing 44provided by RGD
    Primary source
    RGD:1308984
    See related
    Ensembl:ENSRNOG00000005578 AllianceGenome:RGD:1308984
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Btbd15; RGD1308984
    Summary
    Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. Orthologous to human ZBTB44 (zinc finger and BTB domain containing 44). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 121.6), Muscle (RPKM 119.6) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Zbtb44 in Genome Data Viewer
    Location:
    8q13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (37724237..37782220)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (29466055..29524027)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (32165388..32223341)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene small ubiquitin-related modifier 2-like Neighboring gene ST14 transmembrane serine protease matriptase Neighboring gene amyloid beta precursor like protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC125242

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger and BTB domain-containing protein 44
    Names
    BTB (POZ) domain containing 15
    BTB/POZ domain-containing protein 15

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034942.2 → NP_001030114.1  zinc finger and BTB domain-containing protein 44

      See identical proteins and their annotated locations for NP_001030114.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/Swiss-Prot
      Q3SWU4
      UniProtKB/TrEMBL
      A0A0G2JVS3, A6JYF7
      Related
      ENSRNOP00000069596.2, ENSRNOT00000081145.2
      Conserved Domains (5) summary
      PRK10049
      Location:203 → 322
      pgaA; outer membrane protein PgaA; Provisional
      sd00017
      Location:401 → 421
      ZF_C2H2; C2H2 Zn finger [structural motif]
      cd18228
      Location:15 → 130
      BTB_POZ_ZBTB44; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in zinc finger and BTB domain-containing protein 44 (ZBTB44)
      pfam00096
      Location:399 → 421
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:413 → 438
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      37724237..37782220
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265734.1 → XP_063121804.1  zinc finger and BTB domain-containing protein 44 isoform X4

    2. XM_063265733.1 → XP_063121803.1  zinc finger and BTB domain-containing protein 44 isoform X4

    3. XM_006242769.5 → XP_006242831.1  zinc finger and BTB domain-containing protein 44 isoform X2

      Conserved Domains (7) summary
      smart00225
      Location:32 → 128
      BTB; Broad-Complex, Tramtrack and Bric a brac
      COG5048
      Location:351 → 431
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:383 → 403
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:471 → 493
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:381 → 403
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:21 → 125
      BTB; BTB/POZ domain
      pfam13465
      Location:395 → 420
      zf-H2C2_2; Zinc-finger double domain

    4. XM_006242768.5 → XP_006242830.1  zinc finger and BTB domain-containing protein 44 isoform X1

      UniProtKB/TrEMBL
      A0A8L2Q3C2
      Related
      ENSRNOP00000007539.6
      Conserved Domains (7) summary
      smart00225
      Location:32 → 128
      BTB; Broad-Complex, Tramtrack and Bric a brac
      COG5048
      Location:383 → 449
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:401 → 421
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00020
      Location:489 → 511
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:399 → 421
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:21 → 125
      BTB; BTB/POZ domain
      pfam13465
      Location:413 → 438
      zf-H2C2_2; Zinc-finger double domain

    5. XM_063265731.1 → XP_063121801.1  zinc finger and BTB domain-containing protein 44 isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3SWU4.1 GenPept UniProtKB/Swiss-Prot:Q3SWU4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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