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    Map3k19 mitogen-activated protein kinase kinase kinase 19 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 289001, updated on 11-Apr-2024

    Summary

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    Symbol
    Map3k19provided by RGD
    Full Name
    mitogen-activated protein kinase kinase kinase 19provided by RGD
    Primary source
    RGD:1566400
    See related
    Ensembl:ENSRNOG00000003952 AllianceGenome:RGD:1566400
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Ysk4; RGD1566400; AABR07020879.1
    Summary
    Orthologous to human MAP3K19 (mitogen-activated protein kinase kinase kinase 19). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Lung (RPKM 18.0), Brain (RPKM 4.2) and 2 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Map3k19 in Genome Data Viewer
    Location:
    13q13
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (41852633..41896078, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (39300150..39343502, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (44524055..44553197, complement)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene aminocarboxymuconate semialdehyde decarboxylase Neighboring gene cyclin T2 Neighboring gene small nucleolar RNA SNORA36 family Neighboring gene RAB3 GTPase activating protein catalytic subunit 1 Neighboring gene zinc finger RANBP2-type containing 3 Neighboring gene microRNA 3473

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase kinase 19
    Names
    YSK4 Sps1/Ste20-related kinase homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      41852633..41896078 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039091284.2 → XP_038947212.1  mitogen-activated protein kinase kinase kinase 19

      UniProtKB/TrEMBL
      F1LVM0
      Related
      ENSRNOP00000005244.7
      Conserved Domains (2) summary
      cd06631
      Location:1244 → 1509
      STKc_YSK4; Catalytic domain of the Serine/Threonine Kinase, Yeast Sps1/Ste20-related Kinase 4
      sd00045
      Location:44 → 74
      ANK; ANK repeat [structural motif]

    RNA

    1. XR_010056991.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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