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    Asz1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 170578, updated on 2-May-2024

    Summary

    Official Symbol
    Asz1provided by RGD
    Official Full Name
    ankyrin repeat, SAM and basic leucine zipper domain containing 1provided by RGD
    Primary source
    RGD:621579
    See related
    Ensembl:ENSRNOG00000060343 AllianceGenome:RGD:621579
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Gasz
    Summary
    Predicted to be involved in gamete generation and piRNA metabolic process. Predicted to be located in cytoplasm. Predicted to be active in pi-body. Orthologous to human ASZ1 (ankyrin repeat, SAM and basic leucine zipper domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 38.6) See more
    Orthologs
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    Genomic context

    See Asz1 in Genome Data Viewer
    Location:
    4q22
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (47366373..47421976, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (46400485..46456085, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (45358574..45414177, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene suppression of tumorigenicity 7 Neighboring gene uncharacterized LOC134486733 Neighboring gene Wnt family member 2 Neighboring gene CF transmembrane conductance regulator Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in male meiotic nuclear division ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulatory ncRNA-mediated gene silencing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retrotransposon silencing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in pi-body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in pi-body ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_130750.1NP_570106.1  ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

      See identical proteins and their annotated locations for NP_570106.1

      Status: PROVISIONAL

      Source sequence(s)
      AF461260
      UniProtKB/TrEMBL
      A0A0G2K840, A6IE39, Q8VHF9
      Related
      ENSRNOP00000074460.1, ENSRNOT00000091311.2
      Conserved Domains (4) summary
      cd09521
      Location:273333
      SAM_ASZ1; SAM domain of ASZ1 subfamily
      COG0666
      Location:78214
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:151179
      ANK; ANK repeat [structural motif]
      pfam13637
      Location:4799
      Ank_4; Ankyrin repeats (many copies)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      47366373..47421976 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)