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    Sec14l5 SEC14-like lipid binding 5 [ Mus musculus (house mouse) ]

    Gene ID: 665119, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Sec14l5provided by MGI
    Official Full Name
    SEC14-like lipid binding 5provided by MGI
    Primary source
    MGI:MGI:3616084
    See related
    Ensembl:ENSMUSG00000091712 AllianceGenome:MGI:3616084
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Is expressed in brain. Orthologous to human SEC14L5 (SEC14 like lipid binding 5). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in cerebellum adult (RPKM 6.0), cortex adult (RPKM 3.5) and 9 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Sec14l5 in Genome Data Viewer
    Location:
    16 A1; 16 2.5 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (4964758..5005135)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (5146906..5187271)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene ubinuclein 1 Neighboring gene predicted gene, 23483 Neighboring gene transmembrane protein 126A pseudogene Neighboring gene periplakin Neighboring gene N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Neighboring gene expressed sequence AU021092 Neighboring gene microRNA 6364

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of novel radiation-induced p53-dependent transcripts extensively regulated during mouse brain development. Quintens R, et al. Biol Open, 2015 Feb 13. PMID 25681390, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, et al. Nature, 2002 Dec 5. PMID 12466851
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SEC14-like protein 5
    Names
    SEC14-like 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127725.2 → NP_001121197.1  SEC14-like protein 5 isoform 1

      See identical proteins and their annotated locations for NP_001121197.1

      Status: VALIDATED

      Source sequence(s)
      AC124576
      Consensus CDS
      CCDS49752.1
      UniProtKB/TrEMBL
      B2RXM5
      Related
      ENSMUSP00000128063.2, ENSMUST00000165810.2
      Conserved Domains (3) summary
      smart00516
      Location:306 → 479
      SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
      smart01100
      Location:243 → 288
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      pfam04707
      Location:17 → 173
      PRELI; PRELI-like family

    2. NM_001417648.1 → NP_001404577.1  SEC14-like protein 5 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC124576
      UniProtKB/TrEMBL
      B2RXM5
      Related
      ENSMUSP00000155164.2, ENSMUST00000230616.2

    3. NM_001417649.1 → NP_001404578.1  SEC14-like protein 5 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC124576
      UniProtKB/TrEMBL
      B2RXM5

    4. NM_001417650.1 → NP_001404579.1  SEC14-like protein 5 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC124576

    5. NM_001417651.1 → NP_001404580.1  SEC14-like protein 5 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC124576

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      4964758..5005135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006522466.5 → XP_006522529.1  SEC14-like protein 5 isoform X3

      Conserved Domains (4) summary
      smart00516
      Location:306 → 436
      SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
      smart01100
      Location:243 → 288
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      pfam04707
      Location:17 → 173
      PRELI; PRELI-like family
      cl18951
      Location:179 → 309
      Amidase

    RNA

    1. XR_001781850.3 RNA Sequence

    2. XR_384588.5 RNA Sequence

    3. XR_004939205.1 RNA Sequence

    4. XR_004939207.1 RNA Sequence

    5. XR_384587.5 RNA Sequence

    6. XR_004939208.1 RNA Sequence

    7. XR_004939206.1 RNA Sequence

    8. XR_004939204.1 RNA Sequence

    9. XR_001781851.3 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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