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    G0S2 G0/G1 switch 2 [ Homo sapiens (human) ]

    Gene ID: 50486, updated on 8-Jul-2021

    Summary

    Official Symbol
    G0S2provided by HGNC
    Official Full Name
    G0/G1 switch 2provided by HGNC
    Primary source
    HGNC:HGNC:30229
    See related
    Ensembl:ENSG00000123689 MIM:614447
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Biased expression in fat (RPKM 569.0), bone marrow (RPKM 395.4) and 4 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See G0S2 in Genome Data Viewer
    Location:
    1q32.2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (209675412..209676390)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (209848757..209849735)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107985256 Neighboring gene calcium/calmodulin dependent protein kinase IG Neighboring gene laminin subunit beta 3 Neighboring gene microRNA 4260 Neighboring gene HSD11B1 antisense RNA 1 Neighboring gene hydroxysteroid 11-beta dehydrogenase 1 Neighboring gene adenosine A2b receptor pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Envelope transmembrane glycoprotein gp41 env A synthetic peptide corresponding to the immunosuppressive domain (amino acids 574-592) of HIV-1 gp41 upregulates the expression of G0/G1switch 2 (G0S2) in peptide-treated PBMCs PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in lipid droplet TAS
    Traceable Author Statement
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    G0/G1 switch protein 2
    Names
    G0/G1 switch regulatory protein 2
    G0/G1switch 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_015714.4NP_056529.1  G0/G1 switch protein 2

      See identical proteins and their annotated locations for NP_056529.1

      Status: VALIDATED

      Source sequence(s)
      AV709160, BM788126
      Consensus CDS
      CCDS1488.1
      UniProtKB/Swiss-Prot
      P27469
      Related
      ENSP00000355996.4, ENST00000367029.5
      Conserved Domains (1) summary
      pfam15103
      Location:1103
      G0-G1_switch_2; G0/G1 switch protein 2

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      209675412..209676390
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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