U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    MARK1 microtubule affinity regulating kinase 1 [ Homo sapiens (human) ]

    Gene ID: 4139, updated on 3-Apr-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    MARK1provided by HGNC
    Official Full Name
    microtubule affinity regulating kinase 1provided by HGNC
    Primary source
    HGNC:HGNC:6896
    See related
    Ensembl:ENSG00000116141 MIM:606511; AllianceGenome:HGNC:6896
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MARK; Par1c; Par-1c
    Summary
    Enables several functions, including ATP binding activity; phospholipid binding activity; and protein kinase activity. Involved in intracellular signal transduction and protein phosphorylation. Located in cytoplasm; dendrite; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in brain (RPKM 4.9), testis (RPKM 3.5) and 21 other tissues See more
    Orthologs
    mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See MARK1 in Genome Data Viewer
    Location:
    1q41
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (220528136..220664461)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (219767527..219904166)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (220701478..220837803)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105372928 Neighboring gene long intergenic non-protein coding RNA 2779 Neighboring gene Sharpr-MPRA regulatory region 1437 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1825 Neighboring gene RNA, 7SL, cytoplasmic 464, pseudogene Neighboring gene histone deacetylase 1 pseudogene 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:220856220-220856720 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1826 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr1:220869747-220870946 Neighboring gene chromosome 1 open reading frame 115 Neighboring gene uncharacterized LOC124904516 Neighboring gene mitochondrial amidoxime reducing component 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain. Emptage RP, et al. Structure, 2018 Aug 7. PMID 30099988, Free PMC Article
    2. Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase. Emptage RP, et al. Biochem J, 2017 Feb 1. PMID 27879374, Free PMC Article
    3. Mark/Par-1 marking the polarity of migrating neurons. Reiner O, et al. Adv Exp Med Biol, 2014. PMID 24243102
    4. Structure and regulation of MARK, a kinase involved in abnormal phosphorylation of Tau protein. Timm T, et al. BMC Neurosci, 2008 Dec 3. PMID 19090997, Free PMC Article
    5. MicroRNA-23a promotes colorectal cancer cell migration and proliferation by targeting at MARK1. Tang X, et al. Acta Biochim Biophys Sin (Shanghai), 2019 Jul 10. PMID 31281935

    See all (77) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Microtubule affinity regulating kinase 1 (MARK1) is a direct target of miR-23a in colorectal cancer (CRC) cells.
      Title: MicroRNA-23a promotes colorectal cancer cell migration and proliferation by targeting at MARK1.
    2. Structural basis for MARK1 kinase autoinhibition by its KA1 domain has been uncovered.
      Title: Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain.
    3. Low MARK1 is associated with cervical cancer.
      Title: MARK1 is a Novel Target for miR-125a-5p: Implications for Cell Migration in Cervical Tumor Cells.
    4. Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase have been described.
      Title: Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase.
    5. the positioning of MARK/Par-1 at the crosstalk of regulating cytoskeletal dynamics allows its participation in neuronal polarity decisions. [review]
      Title: Mark/Par-1 marking the polarity of migrating neurons.
    6. LKB1 acts through its substrates of the microtubule affinity-regulating kinase family to regulate the localization of the polarity determinant Scribble and the activity of the core Hippo kinases
      Title: A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP pathway.
    7. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    8. In the Australian GWAS, the SNP rs7530302 near MARK1 on chromosome 1 (p=1.90 x 10(-9) achieved genomewide significance for comorbid AD/ND.
      Title: A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.
    9. Data show that protein kinases of the MARK family phosphorylate tau protein in its repeat domain and thereby regulate its affinity for microtubules and affect the aggregation of tau into Alzheimer paired helical filaments.
      Title: Structure and regulation of MARK, a kinase involved in abnormal phosphorylation of Tau protein.
    10. MARK1 was overexpressed in a prefrontal region in the brains of patients with Autism spectrum disorders.
      Title: Convergent evidence identifying MAP/microtubule affinity-regulating kinase 1 (MARK1) as a susceptibility gene for autism.
    Submit: New GeneRIF Correction See all GeneRIFs (12)

    Phenotypes

    Go to the top of the page Help

    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genes linked to energy metabolism and immunoregulatory mechanisms are associated with subcutaneous adipose tissue distribution in HIV-infected men.
    EBI GWAS Catalog
    Genome-wide association study in bipolar patients stratified by co-morbidity.
    EBI GWAS Catalog

    Variation

    Go to the top of the page Help

    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    HIV-1 interactions

    Go to the top of the page Help

    Replication interactions

    Interaction Pubs
    Knockdown of MAP/microtubule affinity-regulating kinase 1 (MARK1) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • KIAA1477, MGC126512, MGC126513

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables ATP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidic acid binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylinositol-4,5-bisphosphate binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylserine binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables tau protein binding NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables tau-protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables tau-protein kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables tau-protein kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables tau-protein kinase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in establishment of mitochondrion localization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular signal transduction IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in negative regulation of epithelial to mesenchymal transition IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of negative regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuron migration ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in peptidyl-serine phosphorylation NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of positive regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of dendrite development ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of neuron projection development ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in microtubule cytoskeleton TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    serine/threonine-protein kinase MARK1
    Names
    MAP/microtubule affinity-regulating kinase 1
    PAR1 homolog c
    NP_001273053.1
    NP_001273055.1
    NP_001273057.1
    NP_001273058.1
    NP_061120.3
    XP_005273191.1
    XP_006711389.1
    XP_011507863.1
    XP_011507864.1
    XP_016856794.1
    XP_024302858.1
    XP_047276800.1
    XP_054192613.1
    XP_054192614.1
    XP_054192615.1
    XP_054192616.1
    XP_054192617.1
    XP_054192618.1
    XP_054192619.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001286124.2 → NP_001273053.1  serine/threonine-protein kinase MARK1 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC096640, AK314614, AL592406, BC068608, CA412112
      Consensus CDS
      CCDS73033.1
      UniProtKB/TrEMBL
      A0A087X0I6, X5DNR8
      Related
      ENSP00000483424.1, ENST00000611084.4
      Conserved Domains (4) summary
      cd12196
      Location:697 → 794
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:60 → 311
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:331 → 371
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cd14072
      Location:59 → 311
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    2. NM_001286126.2 → NP_001273055.1  serine/threonine-protein kinase MARK1 isoform 3

      See identical proteins and their annotated locations for NP_001273055.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice site and lacks an exon in the 3' coding region but maintains the reading frame, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1.
      Source sequence(s)
      AC096640, AK295506, AL592406, BC068608, CA412112
      Consensus CDS
      CCDS73034.1
      UniProtKB/TrEMBL
      B4DIB3, X5DNR8
      Related
      ENSP00000386017.2, ENST00000402574.5
      Conserved Domains (4) summary
      cd12196
      Location:681 → 778
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:60 → 311
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:331 → 371
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cd14072
      Location:59 → 311
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    3. NM_001286128.2 → NP_001273057.1  serine/threonine-protein kinase MARK1 isoform 4

      See identical proteins and their annotated locations for NP_001273057.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 4, which is shorter than isoform 1.
      Source sequence(s)
      AB040910, AC096640, AL592406, BC068608, CA412112
      Consensus CDS
      CCDS65789.1
      UniProtKB/TrEMBL
      A0A7I2V550
      Related
      ENSP00000355885.4, ENST00000366918.8
      Conserved Domains (4) summary
      cd12196
      Location:659 → 756
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:60 → 289
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:309 → 349
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cl21453
      Location:59 → 289
      PKc_like; Protein Kinases, catalytic domain

    4. NM_001286129.2 → NP_001273058.1  serine/threonine-protein kinase MARK1 isoform 5

      See identical proteins and their annotated locations for NP_001273058.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 3' UTR and has multiple coding region differences, compared to variant 1, one of which results in a frameshift. The resulting protein (isoform 5) has a distinct C-terminus and is shorter than isoform 1.
      Source sequence(s)
      AC096640, BC068608
      UniProtKB/TrEMBL
      A0A7I2V4P8
      Conserved Domains (1) summary
      cl21453
      Location:59 → 105
      PKc_like; Protein Kinases, catalytic domain

    5. NM_018650.5 → NP_061120.3  serine/threonine-protein kinase MARK1 isoform 2

      See identical proteins and their annotated locations for NP_061120.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AC096640, AL592406, BC068608, BC113869, CA412112
      Consensus CDS
      CCDS31029.2
      UniProtKB/Swiss-Prot
      D3DTB0, D3DTB1, Q2HIY1, Q5VTF9, Q5VTG0, Q96SW9, Q9P0L2, Q9P251
      UniProtKB/TrEMBL
      X5DNR8
      Related
      ENSP00000355884.5, ENST00000366917.6
      Conserved Domains (4) summary
      cd12196
      Location:696 → 793
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:60 → 311
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:331 → 371
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cd14072
      Location:59 → 311
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      220528136..220664461
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017001305.3 → XP_016856794.1  serine/threonine-protein kinase MARK1 isoform X5

      UniProtKB/TrEMBL
      A0A7I2YQC1
      Related
      ENSP00000503257.1, ENST00000678435.1
      Conserved Domains (4) summary
      cd12196
      Location:587 → 684
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:1 → 201
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:221 → 261
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cl21453
      Location:1 → 201
      PKc_like; Protein Kinases, catalytic domain

    2. XM_005273134.6 → XP_005273191.1  serine/threonine-protein kinase MARK1 isoform X3

      See identical proteins and their annotated locations for XP_005273191.1

      UniProtKB/TrEMBL
      X5D2M4, X5DNR8
      Conserved Domains (4) summary
      cd12196
      Location:682 → 779
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:60 → 311
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:331 → 371
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cd14072
      Location:59 → 311
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    3. XM_024447090.2 → XP_024302858.1  serine/threonine-protein kinase MARK1 isoform X6

      Conserved Domains (1) summary
      cd14072
      Location:59 → 303
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    4. XM_011509561.4 → XP_011507863.1  serine/threonine-protein kinase MARK1 isoform X1

      UniProtKB/TrEMBL
      X5DNR8
      Conserved Domains (4) summary
      cd12196
      Location:689 → 786
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:52 → 303
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:323 → 363
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cd14072
      Location:51 → 303
      STKc_MARK; Catalytic domain of the Serine/Threonine Kinases, MAP/microtubule affinity-regulating kinases

    5. XM_047420844.1 → XP_047276800.1  serine/threonine-protein kinase MARK1 isoform X2

    6. XM_006711326.5 → XP_006711389.1  serine/threonine-protein kinase MARK1 isoform X4

      UniProtKB/TrEMBL
      A0A7I2YQC1
      Conserved Domains (4) summary
      cd12196
      Location:609 → 706
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:15 → 223
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:243 → 283
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cl21453
      Location:10 → 223
      PKc_like; Protein Kinases, catalytic domain

    7. XM_011509562.4 → XP_011507864.1  serine/threonine-protein kinase MARK1 isoform X5

      UniProtKB/TrEMBL
      A0A7I2YQC1
      Conserved Domains (4) summary
      cd12196
      Location:587 → 684
      MARK1-3_C; C-terminal, kinase associated domain 1 (KA1), a phospholipid binding domain, of microtubule affinity-regulating kinases 1-3
      smart00220
      Location:1 → 201
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14405
      Location:221 → 261
      UBA_MARK1; UBA domain found in serine/threonine-protein kinase MARK1 and similar proteins
      cl21453
      Location:1 → 201
      PKc_like; Protein Kinases, catalytic domain

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      219767527..219904166
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054336642.1 → XP_054192617.1  serine/threonine-protein kinase MARK1 isoform X5

    2. XM_054336640.1 → XP_054192615.1  serine/threonine-protein kinase MARK1 isoform X3

      UniProtKB/TrEMBL
      X5D2M4

    3. XM_054336644.1 → XP_054192619.1  serine/threonine-protein kinase MARK1 isoform X6

    4. XM_054336638.1 → XP_054192613.1  serine/threonine-protein kinase MARK1 isoform X1

    5. XM_054336639.1 → XP_054192614.1  serine/threonine-protein kinase MARK1 isoform X2

    6. XM_054336641.1 → XP_054192616.1  serine/threonine-protein kinase MARK1 isoform X4

    7. XM_054336643.1 → XP_054192618.1  serine/threonine-protein kinase MARK1 isoform X5

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9P0L2.2 GenPept UniProtKB/Swiss-Prot:Q9P0L2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous