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    Zmynd12 zinc finger, MYND domain containing 12 [ Mus musculus (house mouse) ]

    Gene ID: 332934, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Zmynd12provided by MGI
    Official Full Name
    zinc finger, MYND domain containing 12provided by MGI
    Primary source
    MGI:MGI:2140259
    See related
    Ensembl:ENSMUSG00000070806 AllianceGenome:MGI:2140259
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Orthologous to human ZMYND12 (zinc finger MYND-type containing 12). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 37.9), ovary adult (RPKM 3.4) and 2 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zmynd12 in Genome Data Viewer
    Location:
    4 D2.1; 4 55.38 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (119279881..119311096)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (119422611..119453899)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 30 Neighboring gene lactate dehydrogenase A, pseudogene 2 Neighboring gene STARR-seq mESC enhancer starr_11233 Neighboring gene phosphopantothenoylcysteine synthetase Neighboring gene STARR-positive B cell enhancer ABC_E2708 Neighboring gene ribosomal modification protein rimK-like family member A Neighboring gene STARR-seq mESC enhancer starr_11235 Neighboring gene cyclin H pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Role of the ANKMY2-FKBP38 axis in regulation of the Sonic hedgehog (Shh) signaling pathway. Saita S, et al. J Biol Chem, 2014 Sep 12. PMID 25077969, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in flagellated sperm motility ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in sperm axoneme assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in sperm flagellum ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger MYND domain-containing protein 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014900.2 → NP_001014900.2  zinc finger MYND domain-containing protein 12

      See identical proteins and their annotated locations for NP_001014900.2

      Status: VALIDATED

      Source sequence(s)
      AL645563, BC147848
      Consensus CDS
      CCDS18582.1
      UniProtKB/TrEMBL
      A2BGJ5, Q56GB0
      Related
      ENSMUSP00000092414.5, ENSMUST00000094819.5
      Conserved Domains (3) summary
      sd00006
      Location:132 → 162
      TPR; TPR repeat [structural motif]
      pfam01753
      Location:17 → 54
      zf-MYND; MYND finger
      pfam13424
      Location:92 → 156
      TPR_12; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      119279881..119311096
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503191.4 → XP_006503254.1  zinc finger MYND domain-containing protein 12 isoform X1

      Conserved Domains (3) summary
      sd00006
      Location:132 → 162
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:92 → 156
      TPR_12; Tetratricopeptide repeat
      pfam01753
      Location:17 → 54
      zf-MYND; MYND finger
    Nucleotide Protein Strain
    Heading Accession and Version

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