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    Zfp763 zinc finger protein 763 [ Mus musculus (house mouse) ]

    Gene ID: 73451, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Zfp763provided by MGI
    Official Full Name
    zinc finger protein 763provided by MGI
    Primary source
    MGI:MGI:1920701
    See related
    Ensembl:ENSMUSG00000067430 AllianceGenome:MGI:1920701
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700065O13Rik
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Is expressed in central nervous system; ganglia; and retina. Orthologous to human ZNF778 (zinc finger protein 778). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E18 (RPKM 5.0), CNS E14 (RPKM 4.2) and 20 other tissues See more
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    Genomic context

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    See Zfp763 in Genome Data Viewer
    Location:
    17 B1; 17 17.98 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (33235838..33252355, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (33016864..33033381, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7516 Neighboring gene zinc finger protein 472 Neighboring gene zinc finger protein 952 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33170086-33170195 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33170311-33170494 Neighboring gene STARR-seq mESC enhancer starr_42403 Neighboring gene PHD finger protein 8 like Neighboring gene STARR-positive B cell enhancer ABC_E4206 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:33226471-33226658 Neighboring gene zinc finger protein 563

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    2. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 763

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028543.3 → NP_082819.1  zinc finger protein 763

      See identical proteins and their annotated locations for NP_082819.1

      Status: PROVISIONAL

      Source sequence(s)
      CT033772
      Consensus CDS
      CCDS37560.1
      UniProtKB/TrEMBL
      Q8BIC7
      Related
      ENSMUSP00000084936.5, ENSMUST00000087654.5
      Conserved Domains (5) summary
      smart00349
      Location:10 → 50
      KRAB; krueppel associated box
      COG5048
      Location:221 → 570
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:393 → 413
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:10 → 49
      KRAB; KRAB box
      pfam13465
      Location:406 → 430
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      33235838..33252355 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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