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    RPL26A ribosomal 60S subunit protein L26A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851058, updated on 17-May-2024

    Summary

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    Gene symbol
    RPL26A
    Gene description
    ribosomal 60S subunit protein L26A
    Primary source
    FungiDB:YLR344W
    Locus tag
    YLR344W
    See related
    SGD:S000004336; AllianceGenome:SGD:S000004336; VEuPathDB:YLR344W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables RNA binding activity. A structural constituent of ribosome. Involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 11. Orthologous to human RPL26 (ribosomal protein L26) and RPL26L1 (ribosomal protein L26 like 1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See RPL26A in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    2
    Sequence:
    Chromosome: XII; NC_001144.5 (819312..820142)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene 1,3-beta-glucanosyltransferase Neighboring gene tRNA-Arg Neighboring gene bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase Neighboring gene Cis1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Indirect monitoring of TORC1 signalling pathway reveals molecular diversity among different yeast strains. Kessi-Pérez EI, et al. Yeast, 2019 Jan. PMID 30094872
    2. Yeast ribosomal protein L26 is located at the ribosomal subunit interface as determined by chemical cross-linking. Villarreal J Jr, et al. Biochimie, 1998 Apr. PMID 9672752
    3. Saccharomyces cerevisiae ribosomal protein L26 is not essential for ribosome assembly and function. Babiano R, et al. Mol Cell Biol, 2012 Aug. PMID 22688513, Free PMC Article
    4. Association of ribosomal proteins with nascent transcripts in S. cerevisiae. Schroder PA, et al. RNA, 2005 Oct. PMID 16199762, Free PMC Article
    5. Pathway of Hsp70 interactions at the ribosome. Lee K, et al. Nat Commun, 2021 Sep 27. PMID 34580293, Free PMC Article

    See all (89) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Saccharomyces cerevisiae ribosomal protein L26 is not essential for ribosome assembly and function
      Title: Saccharomyces cerevisiae ribosomal protein L26 is not essential for ribosome assembly and function.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytoplasmic translation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in ribosomal large subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in intracellular organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L26A
    NP_013448.1
    • Ribosomal 60S subunit protein L26A; binds to 5.8S rRNA; non-essential even when paralog is also deleted; deletion has minimal affections on ribosome biosynthesis; homologous to mammalian ribosomal protein L26 and bacterial L24; RPL26A has a paralog, RPL26B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      819312..820142
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182233.1 → NP_013448.1  TPA: ribosomal 60S subunit protein L26A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013448.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VYY3, P05743
      UniProtKB/TrEMBL
      C7GRX0, N1NZN4
      Conserved Domains (1) summary
      pfam16906
      Location:9 → 122
      Ribosomal_L26; Ribosomal proteins L26 eukaryotic, L24P archaeal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    3JCT_Y.1
    4V88_BY.1
    4V88_DY.1
    4V8T_Y.1
    5APN_Y.1
    5APO_Y.1
    5FL8_Y.1
    5H4P_Y.1
    5JCS_Y.1
    5T62_l.1
    5T6R_l.1
    5Z3G_c.1
    6ELZ_Y.1
    6EM1_Y.1
    6EM3_Y.1
    6EM4_Y.1
    6EM5_Y.1
    6FT6_Y.1
    6M62_Y.1
    6N8J_Y.1
    6N8K_Y.1
    6N8L_Y.1
    6N8M_l.1
    6N8N_l.1
    6N8O_l.1
    7AZY_q.1
    7BT6_Y.1
    7BTB_Y.1
    7OF1_Y.1
    7OH3_Y.1
    7OHP_Y.1
    7OHQ_Y.1
    7OHR_Y.1
    7OHS_Y.1
    7OHU_Y.1
    7OHV_Y.1
    7OHW_Y.1
    7OHX_Y.1
    7OHY_Y.1
    P05743.3

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