Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Defb2 defensin beta 2 [ Mus musculus (house mouse) ]

    Gene ID: 13215, updated on 23-Jun-2021

    Summary

    Official Symbol
    Defb2provided by MGI
    Official Full Name
    defensin beta 2provided by MGI
    Primary source
    MGI:MGI:1338754
    See related
    Ensembl:ENSMUSG00000006570
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BD-2
    Expression
    Restricted expression toward genital fat pad adult (RPKM 84.7) See more
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Defb2 in Genome Data Viewer
    Location:
    8 A2; 8 10.45 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (22329942..22333498)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (21839926..21843482)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (22950398..22953954)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene 15316 Neighboring gene defensin beta 50 Neighboring gene defensin beta 10 Neighboring gene defensin beta 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Markers

    Clone Names

    • MGC129140, MGC129141

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables CCR6 chemokine receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in defense response to Gram-negative bacterium IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in defense response to Gram-positive bacterium IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in innate immune response in mucosa IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010030.1NP_034160.1  beta-defensin 2 precursor

      See identical proteins and their annotated locations for NP_034160.1

      Status: VALIDATED

      Source sequence(s)
      AJ011800
      Consensus CDS
      CCDS40284.1
      UniProtKB/Swiss-Prot
      P82020
      UniProtKB/TrEMBL
      Q32MH3
      Related
      ENSMUSP00000006745.4, ENSMUST00000006745.4
      Conserved Domains (1) summary
      pfam00711
      Location:3668
      Defensin_beta; Beta defensin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      22329942..22333498
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center