Srsf8 serine and arginine rich splicing factor 8 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Srsf8provided by MGI
Official Full Name: serine and arginine rich splicing factor 8provided by MGI
Primary source: MGI:MGI:3045300
See related: Ensembl:ENSMUSG00000060673 AllianceGenome:MGI:3045300
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 4930595M18Rik
Summary: Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be active in cytoplasm and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: X B; X 38.38 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (80463181..80501728, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (81419575..81458122, complement)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytosol	ISO Inferred from Sequence Orthology more info
is_active_in nuclear speck	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear speck	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: uncharacterized protein LOC245492

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_173435.3 → NP_775611.2 uncharacterized protein LOC245492

See identical proteins and their annotated locations for NP_775611.2

Status: VALIDATED

Source sequence(s)

AK029824, BB616016

Consensus CDS

CCDS53123.1

UniProtKB/TrEMBL

A2RRY9, Q8CDN0

Related

ENSMUSP00000078984.3, ENSMUST00000080083.3

Conserved Domains (3) summary

COG0724
Location:14 → 176

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

pfam13639
Location:775 → 816

zf-RING_2; Ring finger domain

cl17169
Location:16 → 88

RRM_SF; RNA recognition motif (RRM) superfamily