Irgq immunity-related GTPase Q [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Irgqprovided by RGD
Official Full Name: immunity-related GTPase Qprovided by RGD
Primary source: RGD:1309409
See related: Ensembl:ENSRNOG00000070901 AllianceGenome:RGD:1309409
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1309409
Summary: Predicted to enable GTP binding activity. Orthologous to human IRGQ (immunity related GTPase Q). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Brain (RPKM 91.9), Kidney (RPKM 59.4) and 9 other tissues See more
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 1q21

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (89251846..89259799)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (80123925..80131881)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (81395922..81403872)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: immunity-related GTPase family Q protein

Names: immunity-related GTPase family, Q

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001135742.4 → NP_001129214.3 immunity-related GTPase family Q protein

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/TrEMBL

A0A8I5ZUT2

Related

ENSRNOP00000082584.1, ENSRNOT00000119508.1

Conserved Domains (2) summary

cd00267
Location:3 → 62

ABC_ATPase; ATP-binding cassette transporter nucleotide-binding domain

cl38936
Location:224 → 286

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086019.1 Reference GRCr8

Range

89251846..89259799

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006228410.5 → XP_006228472.2 immunity-related GTPase family Q protein isoform X1

Conserved Domains (2) summary

cd00267
Location:13 → 72

ABC_ATPase; ATP-binding cassette transporter nucleotide-binding domain

pfam05049
Location:204 → 296

IIGP; Interferon-inducible GTPase (IIGP)