U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FCHO1 FCH and mu domain containing endocytic adaptor 1 [ Homo sapiens (human) ]

    Gene ID: 23149, updated on 3-Apr-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FCHO1provided by HGNC
    Official Full Name
    FCH and mu domain containing endocytic adaptor 1provided by HGNC
    Primary source
    HGNC:HGNC:29002
    See related
    Ensembl:ENSG00000130475 MIM:613437; AllianceGenome:HGNC:29002
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    IMD76
    Summary
    Enables AP-2 adaptor complex binding activity. Involved in clathrin coat assembly and clathrin-dependent endocytosis. Located in cytosol; nucleoplasm; and plasma membrane. Is active in clathrin-coated pit. Implicated in primary immunodeficiency disease. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in lymph node (RPKM 7.7), spleen (RPKM 6.3) and 14 other tissues See more
    Orthologs
    mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FCHO1 in Genome Data Viewer
    Location:
    19p13.11
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (17747744..17788561)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (17881862..17922647)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (17858553..17899370)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:17715726-17716630 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:17716631-17717535 Neighboring gene unc-13 homolog A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14280 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14281 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:17797343-17798304 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:17798305-17799265 Neighboring gene ReSE screen-validated silencer GRCh37_chr19:17812168-17812395 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:17828319-17828820 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10358 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14282 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14283 Neighboring gene uncharacterized LOC124904649 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:17849672-17850172 Neighboring gene microtubule associated protein 1S Neighboring gene Sharpr-MPRA regulatory region 7159 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10359 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr19:17864444-17864964 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr19:17864965-17865484 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14284 Neighboring gene MPRA-validated peak3395 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:17877027-17877564 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14285 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:17905145-17905842 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:17905843-17906540 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 Neighboring gene insulin like 3

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. FCH domain only 1 (FCHo1), a potential new biomarker for lung cancer. Park S, et al. Cancer Gene Ther, 2022 Jul. PMID 34413495
    2. Inflammatory Bowel Disease and Guillain Barre Syndrome in FCHO1 Deficiency. Aydemir S, et al. J Clin Immunol, 2021 Aug. PMID 33950325
    3. Human FCHO1 deficiency reveals role for clathrin-mediated endocytosis in development and function of T cells. Łyszkiewicz M, et al. Nat Commun, 2020 Feb 25. PMID 32098969, Free PMC Article
    4. Dynamic behavior of FCHO1 revealed by live-cell imaging microscopy: its possible involvement in clathrin-coated vesicle formation. Sakaushi S, et al. Biosci Biotechnol Biochem, 2007 Jul. PMID 17617719
    5. A clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editing. Umasankar PK, et al. Elife, 2014 Oct 10. PMID 25303365, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FCH domain only 1 (FCHo1), a potential new biomarker for lung cancer.
      Title: FCH domain only 1 (FCHo1), a potential new biomarker for lung cancer.
    2. Inflammatory Bowel Disease and Guillain Barre Syndrome in FCHO1 Deficiency.
      Title: Inflammatory Bowel Disease and Guillain Barre Syndrome in FCHO1 Deficiency.
    3. Liquid-like protein interactions catalyse assembly of endocytic vesicles.
      Title: Liquid-like protein interactions catalyse assembly of endocytic vesicles.
    4. A critical role of FCHO1 in the clathrin-mediated endocytosis and T cells development and function.
      Title: Human FCHO1 deficiency reveals role for clathrin-mediated endocytosis in development and function of T cells.
    5. Fcho1/2Eps15/RAP-2 ternary complexes to facilitate conformational activation of AP-2 by the Fcho1/2 interdomain linker to promote AP-2 cargo engagement.
      Title: Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
    6. The central linker of FCHO proteins acts as an allosteric regulator of the prime endocytic adaptor, AP-2.
      Title: A clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editing.
    7. show that the mu-homology domain of FCHO1/2 represents an endocytic interaction hub
      Title: Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning.
    8. study reports FCHo1/2 were required for plasma membrane clathrin-coated vesicle (CCV) budding & marked sites of CCV formation
      Title: FCHo proteins are nucleators of clathrin-mediated endocytosis.
    9. Involved in clathrin-coated vesicle formation.
      Title: Dynamic behavior of FCHO1 revealed by live-cell imaging microscopy: its possible involvement in clathrin-coated vesicle formation.
    Submit: New GeneRIF Correction

    Phenotypes

    Go to the top of the page Help

    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Immunodeficiency 76
    MedGen: C5543004 OMIM: 619164 GeneReviews: Not available
    		not available

    Variation

    Go to the top of the page Help

    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • KIAA0290

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables AP-2 adaptor complex binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in T cell receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in clathrin coat assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in clathrin coat assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in clathrin-dependent endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in clathrin-dependent endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of T cell activation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in clathrin-coated pit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in clathrin-coated pit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in clathrin-coated pit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT colocalizes_with clathrin-coated vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		  
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    F-BAR domain only protein 1
    Names
    FCH domain only 1
    FCH domain only protein 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001161357.2 → NP_001154829.1  F-BAR domain only protein 1 isoform a

      See identical proteins and their annotated locations for NP_001154829.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a).
      Source sequence(s)
      AC008761, AK303623, BC028021, BI756664, BQ433639
      Consensus CDS
      CCDS59365.1
      UniProtKB/TrEMBL
      A0A0C3SFZ9, A0A8V8TPN1
      Related
      ENSP00000473001.1, ENST00000594202.6
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      cl10970
      Location:627 → 882
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
      cl26464
      Location:253 → 562
      Atrophin-1; Atrophin-1 family

    2. NM_001161358.2 → NP_001154830.1  F-BAR domain only protein 1 isoform b

      See identical proteins and their annotated locations for NP_001154830.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate splice site in the 3' coding region compared to variant 1, that results in a frameshift. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761, AK291410, AK303623, BC041130, BI756664, BQ433639
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Related
      ENSP00000470493.1, ENST00000600676.5
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    3. NM_001161359.2 → NP_001154831.1  F-BAR domain only protein 1 isoform c

      See identical proteins and their annotated locations for NP_001154831.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. This variant (4) also uses an alternate splice site in the 3' coding region compared to variant 1, that results in a frameshift. The resulting isoform (c) is shorter and has a distinct C-terminus compared to isoform a. Variants 4 and 17-19 all encode the same isoform (c).
      Source sequence(s)
      AC008761, AK303623, AK316458, BC041130, BQ433639, DB158605
      Consensus CDS
      CCDS59366.1
      UniProtKB/TrEMBL
      B7ZAZ3
      Related
      ENSP00000472668.1, ENST00000595033.5
      Conserved Domains (3) summary
      PHA03247
      Location:203 → 512
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:577 → 838
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
      cl12013
      Location:1 → 220
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    4. NM_001384370.1 → NP_001371299.1  F-BAR domain only protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Related
      ENSP00000514204.1, ENST00000699207.1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    5. NM_001384371.1 → NP_001371300.1  F-BAR domain only protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Related
      ENSP00000470511.2, ENST00000596309.6
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    6. NM_001384372.1 → NP_001371301.1  F-BAR domain only protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Related
      ENSP00000514180.1, ENST00000699177.1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    7. NM_001384373.1 → NP_001371302.1  F-BAR domain only protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    8. NM_001384374.1 → NP_001371303.1  F-BAR domain only protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Related
      ENSP00000514179.1, ENST00000699176.1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    9. NM_001384375.1 → NP_001371304.1  F-BAR domain only protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    10. NM_001384376.1 → NP_001371305.1  F-BAR domain only protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Related
      ENSP00000469075.2, ENST00000600209.6
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    11. NM_001384377.1 → NP_001371306.1  F-BAR domain only protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    12. NM_001384378.1 → NP_001371307.1  F-BAR domain only protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (13) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    13. NM_001384379.1 → NP_001371308.1  F-BAR domain only protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (14) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    14. NM_001384380.1 → NP_001371309.1  F-BAR domain only protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (15) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    15. NM_001384381.1 → NP_001371310.1  F-BAR domain only protein 1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (16) differs in the 5' UTR compared to variant 2. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    16. NM_001384384.1 → NP_001371313.1  F-BAR domain only protein 1 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (17) differs in the 5' UTR compared to variant 4. Variants 4 and 17-19 all encode the same isoform (c).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS59366.1
      UniProtKB/TrEMBL
      B7ZAZ3
      Conserved Domains (3) summary
      PHA03247
      Location:203 → 512
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:577 → 838
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
      cl12013
      Location:1 → 220
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    17. NM_001384385.1 → NP_001371314.1  F-BAR domain only protein 1 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (18) differs in the 5' UTR compared to variant 4. Variants 4 and 17-19 all encode the same isoform (c).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS59366.1
      UniProtKB/TrEMBL
      B7ZAZ3
      Related
      ENST00000597512.1
      Conserved Domains (3) summary
      PHA03247
      Location:203 → 512
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:577 → 838
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
      cl12013
      Location:1 → 220
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    18. NM_001384386.1 → NP_001371315.1  F-BAR domain only protein 1 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (19) differs in the 5' UTR compared to variant 4. Variants 4 and 17-19 all encode the same isoform (c).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS59366.1
      UniProtKB/TrEMBL
      B7ZAZ3
      Conserved Domains (3) summary
      PHA03247
      Location:203 → 512
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:577 → 838
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
      cl12013
      Location:1 → 220
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    19. NM_001384387.1 → NP_001371316.1  F-BAR domain only protein 1 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC008761
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 881
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    20. NM_001384388.1 → NP_001371317.1  F-BAR domain only protein 1 isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (21) differs in the 5' UTR compared to variant 22. Variants 21 and 22 both encode the same isoform (e).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92560.1
      UniProtKB/TrEMBL
      A0A8V8TMX9, A0A8V8TPN1
      Related
      ENSP00000514200.1, ENST00000699202.1
      Conserved Domains (3) summary
      PHA03247
      Location:240 → 549
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:614 → 875
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
      cl12013
      Location:10 → 257
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    21. NM_001384389.1 → NP_001371318.1  F-BAR domain only protein 1 isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (22) differs in the 5' UTR compared to variant 21. Variants 21 and 22 both encode the same isoform (e).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92560.1
      UniProtKB/TrEMBL
      A0A8V8TMX9, A0A8V8TPN1
      Conserved Domains (3) summary
      PHA03247
      Location:240 → 549
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:614 → 875
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
      cl12013
      Location:10 → 257
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    22. NM_001384390.1 → NP_001371319.1  F-BAR domain only protein 1 isoform f

      Status: VALIDATED

      Source sequence(s)
      AC008761
      UniProtKB/TrEMBL
      B7ZAZ3
      Conserved Domains (3) summary
      PHA03247
      Location:228 → 537
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:602 → 863
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
      cl12013
      Location:10 → 245
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    23. NM_001384391.1 → NP_001371320.1  F-BAR domain only protein 1 isoform g

      Status: VALIDATED

      Source sequence(s)
      AC008761
      UniProtKB/TrEMBL
      A0A8V8TP91
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 759
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    24. NM_001384392.1 → NP_001371321.1  F-BAR domain only protein 1 isoform h

      Status: VALIDATED

      Source sequence(s)
      AC008761
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 533
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:588 → 843
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    25. NM_001384393.1 → NP_001371322.1  F-BAR domain only protein 1 isoform i

      Status: VALIDATED

      Description
      Transcript Variant: This variant (26) encodes isoform i. Variants 26-28 all encode the same isoform (i).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92558.1
      UniProtKB/TrEMBL
      A0A8V8TPN1, M0QYA9
      Related
      ENSP00000514196.1, ENST00000699198.1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 533
      PHA03247; large tegument protein UL36; Provisional
      cd09268
      Location:588 → 849
      FCHo1_MHD; mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins

    26. NM_001384394.1 → NP_001371323.1  F-BAR domain only protein 1 isoform i

      Status: VALIDATED

      Description
      Transcript Variant: This variant (27) differs in the 5' UTR compared to variant 26. Variants 26-28 all encode the same isoform (i).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92558.1
      UniProtKB/TrEMBL
      A0A8V8TPN1, M0QYA9
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 533
      PHA03247; large tegument protein UL36; Provisional
      cd09268
      Location:588 → 849
      FCHo1_MHD; mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins

    27. NM_001384395.1 → NP_001371324.1  F-BAR domain only protein 1 isoform i

      Status: VALIDATED

      Description
      Transcript Variant: This variant (28) differs in the 5' UTR compared to variant 26. Variants 26-28 all encode the same isoform (i).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92558.1
      UniProtKB/TrEMBL
      A0A8V8TPN1, M0QYA9
      Related
      ENSP00000514209.1, ENST00000699213.1
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 533
      PHA03247; large tegument protein UL36; Provisional
      cd09268
      Location:588 → 849
      FCHo1_MHD; mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins

    28. NM_001384396.1 → NP_001371325.1  F-BAR domain only protein 1 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (29) encodes isoform j. Variants 29-35 all encode the same isoform (j).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92559.1
      UniProtKB/TrEMBL
      A0A8V8TNC3, A0A8V8TPN1
      Conserved Domains (2) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      cd09268
      Location:535 → 796
      FCHo1_MHD; mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins

    29. NM_001384397.1 → NP_001371326.1  F-BAR domain only protein 1 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (30) differs in the 5' UTR compared to variant 29. Variants 29-35 all encode the same isoform (j).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92559.1
      UniProtKB/TrEMBL
      A0A8V8TNC3, A0A8V8TPN1
      Conserved Domains (2) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      cd09268
      Location:535 → 796
      FCHo1_MHD; mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins

    30. NM_001384398.1 → NP_001371327.1  F-BAR domain only protein 1 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (31) differs in the 5' UTR compared to variant 29. Variants 29-35 all encode the same isoform (j).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92559.1
      UniProtKB/TrEMBL
      A0A8V8TNC3, A0A8V8TPN1
      Related
      ENSP00000514198.1, ENST00000699200.1
      Conserved Domains (2) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      cd09268
      Location:535 → 796
      FCHo1_MHD; mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins

    31. NM_001384399.1 → NP_001371328.1  F-BAR domain only protein 1 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (32) differs in the 5' UTR compared to variant 29. Variants 29-35 all encode the same isoform (j).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92559.1
      UniProtKB/TrEMBL
      A0A8V8TNC3, A0A8V8TPN1
      Related
      ENSP00000514195.1, ENST00000699197.1
      Conserved Domains (2) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      cd09268
      Location:535 → 796
      FCHo1_MHD; mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins

    32. NM_001384400.1 → NP_001371329.1  F-BAR domain only protein 1 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (33) differs in the 5' UTR compared to variant 29. Variants 29-35 all encode the same isoform (j).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92559.1
      UniProtKB/TrEMBL
      A0A8V8TNC3, A0A8V8TPN1
      Conserved Domains (2) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      cd09268
      Location:535 → 796
      FCHo1_MHD; mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins

    33. NM_001384401.1 → NP_001371330.1  F-BAR domain only protein 1 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (34) differs in the 5' UTR compared to variant 29. Variants 29-35 all encode the same isoform (j).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92559.1
      UniProtKB/TrEMBL
      A0A8V8TNC3, A0A8V8TPN1
      Conserved Domains (2) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      cd09268
      Location:535 → 796
      FCHo1_MHD; mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins

    34. NM_001384402.1 → NP_001371331.1  F-BAR domain only protein 1 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (35) differs in the 5' UTR compared to variant 29. Variants 29-35 all encode the same isoform (j).
      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92559.1
      UniProtKB/TrEMBL
      A0A8V8TNC3, A0A8V8TPN1
      Related
      ENSP00000514212.1, ENST00000699216.1
      Conserved Domains (2) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      cd09268
      Location:535 → 796
      FCHo1_MHD; mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins

    35. NM_001384403.1 → NP_001371332.1  F-BAR domain only protein 1 isoform k

      Status: VALIDATED

      Source sequence(s)
      AC008761
      UniProtKB/TrEMBL
      A0A8V8TPA0
      Conserved Domains (2) summary
      cd07674
      Location:10 → 263
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      cd09268
      Location:520 → 781
      FCHo1_MHD; mu-homology domain (MHD) of F-BAR domain-containing Fer/Cip4 homology domain-only protein 1 (FCH domain only 1 or FCHo1, also known as KIAA0290) and similar proteins

    36. NM_001384404.1 → NP_001371333.1  F-BAR domain only protein 1 isoform l

      Status: VALIDATED

      Source sequence(s)
      AC008761
      Conserved Domains (2) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      cl10970
      Location:535 → 667
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    37. NM_001384405.1 → NP_001371334.1  F-BAR domain only protein 1 isoform m

      Status: VALIDATED

      Source sequence(s)
      AC008761
      UniProtKB/TrEMBL
      A0A8V8TP91
      Related
      ENSP00000514194.1, ENST00000699196.1
      Conserved Domains (3) summary
      PHA03247
      Location:240 → 549
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:614 → 764
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
      cl12013
      Location:10 → 257
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    38. NM_001384406.1 → NP_001371335.1  F-BAR domain only protein 1 isoform n

      Status: VALIDATED

      Source sequence(s)
      AC008761
      Conserved Domains (2) summary
      cl10970
      Location:485 → 617
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
      cl12013
      Location:1 → 220
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    39. NM_001384407.1 → NP_001371336.1  F-BAR domain only protein 1 isoform o

      Status: VALIDATED

      Source sequence(s)
      AC008761
      Consensus CDS
      CCDS92561.1
      UniProtKB/TrEMBL
      A0A8V8TPM7
      Related
      ENSP00000514201.1, ENST00000699203.1
      Conserved Domains (2) summary
      cl10970
      Location:437 → 587
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)
      cl12013
      Location:1 → 220
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

    40. NM_015122.3 → NP_055937.1  F-BAR domain only protein 1 isoform b

      See identical proteins and their annotated locations for NP_055937.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate splice site in the 3' coding region compared to variant 1, that results in a frameshift. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a. Variants 2, 3, and 5-16 all encode the same isoform (b).
      Source sequence(s)
      AC008761, AK303623, BC041130, BQ433639, DB158605
      Consensus CDS
      CCDS32955.1
      UniProtKB/Swiss-Prot
      A6NHE6, A8K5U5, B4E120, O14526, Q05C93, Q8IW22
      UniProtKB/TrEMBL
      A0A8V8TPN1
      Related
      ENSP00000470731.1, ENST00000596536.6
      Conserved Domains (3) summary
      cd07674
      Location:10 → 270
      F-BAR_FCHO1; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of FCH domain Only 1 protein
      PHA03247
      Location:253 → 562
      PHA03247; large tegument protein UL36; Provisional
      cl10970
      Location:627 → 888
      AP_MHD_Cterm; C-terminal domain of adaptor protein (AP) complexes medium mu subunits and its homologs (MHD)

    RNA

    1. NR_169219.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    2. NR_169220.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761
      Related
      ENST00000699205.1

    3. NR_169221.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761
      Related
      ENST00000699201.1

    4. NR_169222.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    5. NR_169223.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    6. NR_169224.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    7. NR_169225.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    8. NR_169226.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    9. NR_169227.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    10. NR_169228.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    11. NR_169229.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    12. NR_169230.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    13. NR_169231.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    14. NR_169232.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    15. NR_169233.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    16. NR_169234.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    17. NR_169235.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    18. NR_169236.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    19. NR_169238.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    20. NR_169239.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761
      Related
      ENST00000699206.1

    21. NR_169240.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    22. NR_169246.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    23. NR_169247.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    24. NR_169248.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    25. NR_169249.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    26. NR_169250.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    27. NR_169251.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    28. NR_169252.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761
      Related
      ENST00000699210.1

    29. NR_169253.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    30. NR_169254.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    31. NR_169255.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    32. NR_169256.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    33. NR_169257.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    34. NR_169258.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    35. NR_169259.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    36. NR_169260.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC008761

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      17747744..17788561
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047438491.1 → XP_047294447.1  F-BAR domain only protein 1 isoform X1

      UniProtKB/TrEMBL
      M0QYA9
      Related
      ENSP00000514197.1, ENST00000699199.1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      17881862..17922647
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054320312.1 → XP_054176287.1  F-BAR domain only protein 1 isoform X1

      UniProtKB/TrEMBL
      M0QYA9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O14526.2 GenPept UniProtKB/Swiss-Prot:O14526

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous