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    naf1 nuclear assembly factor 1 homolog (S. cerevisiae) [ Danio rerio (zebrafish) ]

    Gene ID: 568328, updated on 25-Apr-2024

    Summary

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    Official Symbol
    naf1provided by ZNC
    Official Full Name
    nuclear assembly factor 1 homolog (S. cerevisiae)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4546
    See related
    Ensembl:ENSDARG00000057929 AllianceGenome:ZFIN:ZDB-GENE-030131-4546
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fd12g08; wu:fd12g08; si:dkey-22l11.5
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in box H/ACA snoRNP assembly and ribosome biogenesis. Predicted to act upstream of or within pseudouridine synthesis and rRNA processing. Predicted to be located in nucleus. Predicted to be part of sno(s)RNA-containing ribonucleoprotein complex. Orthologous to human NAF1 (nuclear assembly factor 1 ribonucleoprotein). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See naf1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (10003521..10012303)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (10002570..10011387)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene SET binding factor 1 Neighboring gene transfer RNA tyrosine (anticodon GUA) Neighboring gene coiled-coil domain containing 136b Neighboring gene uncharacterized LOC101885530

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in box H/ACA snoRNP assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within box H/ACA snoRNP assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosome biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of sno(s)RNA-containing ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of sno(s)RNA-containing ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    H/ACA ribonucleoprotein complex non-core subunit NAF1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      10003521..10012303
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021475221.1 → XP_021330896.1  H/ACA ribonucleoprotein complex non-core subunit NAF1

      UniProtKB/TrEMBL
      A0A8M9Q692, F1QXL6
      Related
      ENSDARP00000114221.2, ENSDART00000148105.3
      Conserved Domains (1) summary
      pfam04410
      Location:238 → 389
      Gar1; Gar1/Naf1 RNA binding region

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395230.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      419036..427818
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_691652.6 → XP_696744.2  H/ACA ribonucleoprotein complex non-core subunit NAF1

      UniProtKB/TrEMBL
      A0A8M9Q692, F1QXL6
      Conserved Domains (1) summary
      pfam04410
      Location:238 → 389
      Gar1; Gar1/Naf1 RNA binding region
    Nucleotide Protein Strain
    Heading Accession and Version

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