ovca2 OVCA2 serine hydrolase domain containing [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ovca2provided by ZNC
Official Full Name: OVCA2 serine hydrolase domain containingprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050522-115
See related: Ensembl:ENSDARG00000103748 AllianceGenome:ZFIN:ZDB-GENE-050522-115
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:110011
Summary: Predicted to enable thiolester hydrolase activity. Predicted to be involved in response to retinoic acid. Predicted to be active in cytoplasm and nucleus. Orthologous to human OVCA2 (OVCA2 serine hydrolase domain containing). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (35664129..35668579, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (35720269..35724719, complement)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hydrolase activity	IBA Inferred from Biological aspect of Ancestor more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables thiolester hydrolase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in response to retinoic acid	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: esterase OVCA2

Names: ovarian cancer-associated gene 2 protein homolog; ovarian tumor suppressor candidate 2

NP_001018391.1

EC 3.1.2.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001020555.1 → NP_001018391.1 esterase OVCA2

See identical proteins and their annotated locations for NP_001018391.1

Status: PROVISIONAL

Source sequence(s)

BC095129

UniProtKB/Swiss-Prot

Q503Y4

Related

ENSDARP00000133226.1, ENSDART00000167376.2

Conserved Domains (2) summary

COG0596
Location:99 → 210

MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]

pfam03959
Location:1 → 219

FSH1; Serine hydrolase (FSH1)