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    cog4 component of oligomeric golgi complex 4 [ Danio rerio (zebrafish) ]

    Gene ID: 569049, updated on 11-Apr-2024

    Summary

    Official Symbol
    cog4provided by ZNC
    Official Full Name
    component of oligomeric golgi complex 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060312-33
    See related
    Ensembl:ENSDARG00000054264 AllianceGenome:ZFIN:ZDB-GENE-060312-33
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:136860
    Summary
    Acts upstream of or within proteoglycan metabolic process and skeletal system development. Predicted to be located in Golgi membrane and cytosol. Predicted to be part of Golgi transport complex. Is expressed in nervous system; otic epithelium; otic vesicle protrusion; and pharyngeal arch cartilage. Used to study Saul-Wilson syndrome. Human ortholog(s) of this gene implicated in Saul-Wilson syndrome and congenital disorder of glycosylation type IIj. Orthologous to human COG4 (component of oligomeric golgi complex 4). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See cog4 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (29024286..29039270)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (28753136..28768120)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene docking protein 4 Neighboring gene dynein axonemal assembly factor 1 Neighboring gene neuritin 1-like b Neighboring gene THAP domain containing 11 Neighboring gene glucose-fructose oxidoreductase domain containing 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC136860

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within proteoglycan metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within skeletal system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Golgi transport complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    conserved oligomeric Golgi complex subunit 4
    Names
    COG complex subunit 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039823.1NP_001034912.1  conserved oligomeric Golgi complex subunit 4

      See identical proteins and their annotated locations for NP_001034912.1

      Status: PROVISIONAL

      Source sequence(s)
      BC114292
      UniProtKB/Swiss-Prot
      Q29RB1
      Related
      ENSDARP00000070899.2, ENSDART00000076425.5
      Conserved Domains (1) summary
      pfam08318
      Location:180489
      COG4; COG4 transport protein

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      29024286..29039270
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)