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    DACT3-AS1 DACT3 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 100506068, updated on 10-Oct-2023

    Summary

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    Official Symbol
    DACT3-AS1provided by HGNC
    Official Full Name
    DACT3 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:44120
    See related
    Ensembl:ENSG00000245598 AllianceGenome:HGNC:44120
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Biased expression in testis (RPKM 1.8), brain (RPKM 0.2) and 1 other tissue See more
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    Genomic context

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    See DACT3-AS1 in Genome Data Viewer
    Location:
    19q13.32
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (46660364..46677456)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (49485900..49502996)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (47163621..47180713)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene calmodulin 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14844 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 14845 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:47119779-47120280 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:47120281-47120780 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:47124126-47124640 Neighboring gene prostaglandin I2 receptor Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:47128561-47129061 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10815 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10816 Neighboring gene Sharpr-MPRA regulatory region 2120 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10818 Neighboring gene G protein subunit gamma 8 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10819 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:47157789-47158515 Neighboring gene dishevelled binding antagonist of beta catenin 3 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10820 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10821 Neighboring gene protein kinase D2 Neighboring gene RNA, 7SL, cytoplasmic 364, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:47200828-47201328 Neighboring gene microRNA 320e

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Hypoxia-induced LncRNA DACT3-AS1 upregulates PKM2 to promote metastasis in hepatocellular carcinoma through the HDAC2/FOXA3 pathway. Wang L, et al. Exp Mol Med, 2022 Jun. PMID 35764883, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Hypoxia-induced LncRNA DACT3-AS1 upregulates PKM2 to promote metastasis in hepatocellular carcinoma through the HDAC2/FOXA3 pathway.
      Title: Hypoxia-induced LncRNA DACT3-AS1 upregulates PKM2 to promote metastasis in hepatocellular carcinoma through the HDAC2/FOXA3 pathway.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    General gene information

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    Other Names

    • DACT3 antisense RNA 1 (non-protein coding)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_040041.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AC093503, BC043434
      Related
      ENST00000500689.1

    2. NR_040042.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two exons and includes two alternate exons, compared to variant 1.
      Source sequence(s)
      AC093503, AW269981, AW292135, BX116982
      Related
      ENST00000525008.5

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      46660364..46677456
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      49485900..49502996
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Research Materials