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    zgc:55558 zgc:55558 [ Danio rerio (zebrafish) ]

    Gene ID: 393228, updated on 25-Apr-2024

    Summary

    Official Symbol
    zgc:55558provided by ZNC
    Official Full Name
    zgc:55558provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-740
    See related
    Ensembl:ENSDARG00000013161 AllianceGenome:ZFIN:ZDB-GENE-040426-740
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in Ras protein signal transduction. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brain; heart; liver; pleuroperitoneal region; and trunk musculature. Orthologous to human ERAS (ES cell expressed Ras). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    chromosome: 3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (16664261..16679971)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (16514461..16530171)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 6 member 16a Neighboring gene solute carrier family 17 member 7a Neighboring gene polymerase (DNA directed), delta 1, catalytic subunit Neighboring gene glycogen synthase 1 (muscle)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Clone Names

    • MGC55558

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables G protein activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables GDP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200258.1NP_956552.1  GTPase KRas

      See identical proteins and their annotated locations for NP_956552.1

      Status: PROVISIONAL

      Source sequence(s)
      BC048875
      UniProtKB/TrEMBL
      A0A2R8QFC2, A0A2R8QIQ6, Q7ZUL8
      Related
      ENSDARP00000022638.7, ENSDART00000013816.8
      Conserved Domains (2) summary
      cd04138
      Location:3164
      H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
      smart00173
      Location:16166
      RAS; Ras subfamily of RAS small GTPases

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      16664261..16679971
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394525.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      298784..314494
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)