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    ndufb2 NADH:ubiquinone oxidoreductase subunit B2 [ Danio rerio (zebrafish) ]

    Gene ID: 393764, updated on 27-Mar-2024

    Summary

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    Official Symbol
    ndufb2provided by ZNC
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit B2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1762
    See related
    Ensembl:ENSDARG00000045490 AllianceGenome:ZFIN:ZDB-GENE-040426-1762
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:73329; wu:fb78c03
    Summary
    Predicted to be located in mitochondrial inner membrane. Predicted to be integral component of membrane. Predicted to be part of mitochondrial respiratory chain complex I. Orthologous to human NDUFB2 (NADH:ubiquinone oxidoreductase subunit B2). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See ndufb2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (22480148..22482900)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (22759173..22761925)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene origin recognition complex, subunit 5 Neighboring gene LHFPL tetraspan subfamily member 3 Neighboring gene lysine (K)-specific methyltransferase 2E Neighboring gene lysine (K)-specific demethylase 7Aa Neighboring gene sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Spatio-temporal regulation of Wnt and retinoic acid signaling by tbx16/spadetail during zebrafish mesoderm differentiation. Mueller RL, et al. BMC Genomics, 2010 Sep 9. PMID 20828405, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC73329

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial respiratory chain complex I assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial respiratory chain complex I IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in respirasome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
    Names
    NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
    NP_001161298.1
    NP_957085.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001167826.1 → NP_001161298.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial

      See identical proteins and their annotated locations for NP_001161298.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      BX537168, CB357970
      UniProtKB/TrEMBL
      A0A8M1PBS8, Q6PBN0
      Related
      ENSDARP00000066903.3, ENSDART00000066904.4
      Conserved Domains (1) summary
      pfam14813
      Location:29 → 96
      NADH_B2; NADH dehydrogenase 1 beta subcomplex subunit 2

    2. NM_200791.2 → NP_957085.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial

      See identical proteins and their annotated locations for NP_957085.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      BC059649, BX537168
      UniProtKB/TrEMBL
      A0A8M1PBS8, Q6PBN0
      Related
      ENSDARP00000115006.1, ENSDART00000146272.3
      Conserved Domains (1) summary
      pfam14813
      Location:29 → 96
      NADH_B2; NADH dehydrogenase 1 beta subcomplex subunit 2

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      22480148..22482900
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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