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    STAG3L4 STAG3 cohesin complex component like 4 (pseudogene) [ Homo sapiens (human) ]

    Gene ID: 64940, updated on 17-Jun-2024

    Summary

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    Official Symbol
    STAG3L4provided by HGNC
    Official Full Name
    STAG3 cohesin complex component like 4 (pseudogene)provided by HGNC
    Primary source
    HGNC:HGNC:33887
    See related
    Ensembl:ENSG00000291153 AllianceGenome:HGNC:33887
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    STAG3L4P
    Summary
    Predicted to enable chromatin binding activity. Predicted to be involved in sister chromatid cohesion. Predicted to be part of cohesin complex. Predicted to be active in chromatin and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in thyroid (RPKM 5.7), bone marrow (RPKM 4.5) and 25 other tissues See more
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    Genomic context

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    See STAG3L4 in Genome Data Viewer
    Location:
    7q11.21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (67302638..67321526)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (68522374..68541301)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (66767625..66786513)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene tRNA-yW synthesizing protein 1 homolog Neighboring gene uncharacterized LOC124901665 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr7:66705704-66706246 Neighboring gene speedy/RINGO cell cycle regulator family member E21 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26092 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18220 Neighboring gene PMS1 homolog 2, mismatch repair system component pseudogene 4 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr7:66809463-66810662 Neighboring gene uncharacterized LOC105375337 Neighboring gene long intergenic non-protein coding RNA 1372

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the Williams-Beuren syndrome deletion. Pezzi N, et al. FASEB J, 2000 Mar. PMID 10698974
    2. Genome-wide association study of age at menarche in African-American women. Demerath EW, et al. Hum Mol Genet, 2013 Aug 15. PMID 23599027, Free PMC Article
    3. Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase. Neveu G, et al. Methods, 2012 Dec. PMID 22898364, Free PMC Article
    4. SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity. Shi P, et al. J Immunol, 2020 Jul 1. PMID 32393512
    5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Lamesch P, et al. Genomics, 2007 Mar. PMID 17207965, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association study of age at menarche in African-American women.
    EBI GWAS Catalog

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Other Names

    • STAG3-like protein 4
    • stromal antigen 3 pseudogene
    • stromal antigen 3-like 4 (pseudogene)

    Clone Names

    • FLJ13195

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_040585.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AA012895, AC006480, AK023257, AK307290

    2. NR_040586.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate internal exon, compared to variant 1.
      Source sequence(s)
      AA012895, AC006480, AK023257
      Related
      ENST00000416602.6

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      67302638..67321526
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      68522374..68541301
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_022906.2: Suppressed sequence

      Description
      NM_022906.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8TBR4.1 GenPept UniProtKB/Swiss-Prot:Q8TBR4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials