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    scaper S-phase cyclin A-associated protein in the ER [ Danio rerio (zebrafish) ]

    Gene ID: 100144551, updated on 27-Mar-2024

    Summary

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    Official Symbol
    scaperprovided by ZNC
    Official Full Name
    S-phase cyclin A-associated protein in the ERprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060303-5
    See related
    Ensembl:ENSDARG00000023104 AllianceGenome:ZFIN:ZDB-GENE-060303-5
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable nucleic acid binding activity and zinc ion binding activity. Orthologous to human SCAPER (S-phase cyclin A associated protein in the ER). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See scaper in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (32525130..32739728)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (32113926..32332664)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene sulfide quinone oxidoreductase Neighboring gene CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2a Neighboring gene uncharacterized LOC108181625 Neighboring gene ISL LIM homeobox 2a Neighboring gene electron transfer flavoprotein subunit alpha

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints. Irimia M, et al. Genome Res, 2012 Dec. PMID 22722344, Free PMC Article
    2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    S phase cyclin A-associated protein in the endoplasmic reticulum
    Names
    znf291

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001123047.1 → NP_001116519.1  S phase cyclin A-associated protein in the endoplasmic reticulum

      See identical proteins and their annotated locations for NP_001116519.1

      Status: PROVISIONAL

      Source sequence(s)
      BC160657
      UniProtKB/TrEMBL
      A0A8M1NG13, B1H1L9
      Related
      ENSDARP00000094101.3, ENSDART00000103324.4
      Conserved Domains (6) summary
      smart00451
      Location:710 → 741
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:714 → 736
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00836
      Location:449 → 546
      Stathmin; Stathmin family
      pfam08597
      Location:298 → 393
      eIF3_subunit; Translation initiation factor eIF3 subunit
      pfam15665
      Location:466 → 687
      FAM184; Family with sequence similarity 184, A and B
      pfam16501
      Location:107 → 202
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      32525130..32739728
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005163154.4 → XP_005163211.4  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X1

      UniProtKB/TrEMBL
      A0A8M2BAB5
      Conserved Domains (4) summary
      smart00451
      Location:859 → 890
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:863 → 885
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam16501
      Location:147 → 242
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
      cl26511
      Location:494 → 839
      Neuromodulin_N; Gap junction protein N-terminal region

    2. XM_005163155.4 → XP_005163212.4  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X3

      UniProtKB/TrEMBL
      A0A8M2BA55
      Conserved Domains (4) summary
      smart00451
      Location:750 → 781
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:754 → 776
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam16501
      Location:147 → 242
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
      cl26511
      Location:371 → 730
      Neuromodulin_N; Gap junction protein N-terminal region

    3. XM_021470434.1 → XP_021326109.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X4

      UniProtKB/TrEMBL
      A0A8M9PMK3
      Related
      ENSDARP00000128884.1, ENSDART00000156190.3
      Conserved Domains (4) summary
      smart00451
      Location:859 → 890
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:863 → 885
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam16501
      Location:147 → 242
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
      cl26511
      Location:494 → 839
      Neuromodulin_N; Gap junction protein N-terminal region

    4. XM_005163156.4 → XP_005163213.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X2

      UniProtKB/TrEMBL
      A0A8M2BAI5
      Conserved Domains (5) summary
      smart00451
      Location:819 → 850
      ZnF_U1; U1-like zinc finger
      sd00020
      Location:823 → 845
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00836
      Location:558 → 655
      Stathmin; Stathmin family
      pfam15665
      Location:575 → 796
      FAM184; Family with sequence similarity 184, A and B
      pfam16501
      Location:107 → 202
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
    Nucleotide Protein Strain
    Heading Accession and Version

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