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    sh3yl1 SH3 and SYLF domain containing 1 [ Danio rerio (zebrafish) ]

    Gene ID: 566522, updated on 27-Mar-2024

    Summary

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    Official Symbol
    sh3yl1provided by ZNC
    Official Full Name
    SH3 and SYLF domain containing 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040128-16
    See related
    Ensembl:ENSDARG00000074393 AllianceGenome:ZFIN:ZDB-GENE-040128-16
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:cb1095
    Summary
    Predicted to enable phosphatidylinositol binding activity. Predicted to be active in ruffle membrane. Is expressed in yolk syncytial layer. Orthologous to human SH3YL1 (SH3 and SYLF domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See sh3yl1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (30604506..30652714, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (30587856..30635728, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene NHS-like 1a Neighboring gene si:dkey-190l8.2 Neighboring gene ALK and LTK ligand 2b Neighboring gene zgc:194392

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables phosphatidylinositol binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of ruffle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in ruffle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SH3 domain-containing YSC84-like protein 1
    Names
    SH3 domain containing, Ysc84-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001423240.1 → NP_001410169.1  SH3 domain-containing YSC84-like protein 1

      Status: VALIDATED

      Source sequence(s)
      BX072551, CR407588
      UniProtKB/TrEMBL
      A0A8N7TF62, X1WFC4

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      30604506..30652714 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_689794.9 → XP_694886.2  SH3 domain-containing YSC84-like protein 1 isoform X1

      UniProtKB/TrEMBL
      X1WFC4
      Related
      ENSDARP00000128928.1, ENSDART00000154960.3
      Conserved Domains (2) summary
      cd11525
      Location:11 → 209
      SYLF_SH3YL1_like; The SYLF domain (also called DUF500), a novel lipid-binding module, of SH3 domain containing Ysc84-like 1 (SH3YL1) and similar proteins
      cd11841
      Location:281 → 334
      SH3_SH3YL1_like; Src homology 3 domain of SH3 domain containing Ysc84-like 1 (SH3YL1) protein

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394996.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      231333..262157 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473201.1 → XP_021328876.1  SH3 domain-containing YSC84-like protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q2L4
      Conserved Domains (2) summary
      cd11525
      Location:1 → 180
      SYLF_SH3YL1_like; The SYLF domain (also called DUF500), a novel lipid-binding module, of SH3 domain containing Ysc84-like 1 (SH3YL1) and similar proteins
      cd11841
      Location:252 → 305
      SH3_SH3YL1_like; Src homology 3 domain of SH3 domain containing Ysc84-like 1 (SH3YL1) protein
    Nucleotide Protein Strain
    Heading Accession and Version

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