arvcfb ARVCF delta catenin family member b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: arvcfbprovided by ZNC
Official Full Name: ARVCF delta catenin family member bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-060526-60
See related: Ensembl:ENSDARG00000061688 AllianceGenome:ZFIN:ZDB-GENE-060526-60
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: wu:fc11a08; si:ch211-173n20.1
Summary: Predicted to enable cadherin binding activity. Predicted to be involved in cell-cell adhesion and cell-cell junction assembly. Predicted to act upstream of or within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to be located in cell junction. Predicted to be active in several cellular components, including adherens junction; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in DiGeorge syndrome. Orthologous to human ARVCF (ARVCF delta catenin family member). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	5	NC_007116.7 (26263127..26685396, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	5	NC_007116.6 (25662975..26085264, complement)

Chromosome 5 - NC_007116.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables cadherin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in cell-cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cell-cell adhesion	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in adherens junction	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ARVCF delta catenin family member b; armadillo repeat protein deleted in velo-cardio-facial syndrome

Names: armadillo repeat gene deleted in velocardiofacial syndrome b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001128534.1 → NP_001122006.1 ARVCF delta catenin family member b

See identical proteins and their annotated locations for NP_001122006.1

Status: PROVISIONAL

Source sequence(s)

BX511248, BX890595

UniProtKB/TrEMBL

A0A8M1NHH9, A2BGY1, F1QY26

Related

ENSDARP00000082655.6, ENSDART00000088222.6

Conserved Domains (3) summary

smart00185
Location:422 → 462

ARM; Armadillo/beta-catenin-like repeats

sd00043
Location:393 → 418

ARM; armadillo repeat [structural motif]

cl27106
Location:393 → 506

PLN03200; cellulose synthase-interactive protein; Provisional

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007116.7 Reference GRCz11 Primary Assembly

Range

26263127..26685396 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021476267.1 → XP_021331942.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X2

UniProtKB/TrEMBL

A0A8M9PKF3

Conserved Domains (3) summary

smart00185
Location:461 → 501

ARM; Armadillo/beta-catenin-like repeats

pfam00514
Location:504 → 545

Arm; Armadillo/beta-catenin-like repeat

sd00043
Location:432 → 457

ARM; armadillo repeat [structural motif]
XM_009301526.3 → XP_009299801.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X8

UniProtKB/TrEMBL

A0A8M3ASI4

Conserved Domains (3) summary

cd00020
Location:395 → 513

ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

pfam13646
Location:718 → 786

HEAT_2; HEAT repeats

sd00043
Location:400 → 425

ARM; armadillo repeat [structural motif]
XM_009301527.3 → XP_009299802.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X9

UniProtKB/TrEMBL

A0A8M3B2J8

Conserved Domains (3) summary

cd00020
Location:434 → 552

ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

pfam13646
Location:717 → 785

HEAT_2; HEAT repeats

sd00043
Location:439 → 464

ARM; armadillo repeat [structural motif]
XM_009301522.3 → XP_009299797.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X4

UniProtKB/TrEMBL

A0A8M3AZP1

Conserved Domains (3) summary

cd00020
Location:434 → 552

ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

pfam13646
Location:741 → 809

HEAT_2; HEAT repeats

sd00043
Location:439 → 464

ARM; armadillo repeat [structural motif]
XM_021476268.1 → XP_021331943.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X7

UniProtKB/TrEMBL

A0A8M9PXX9

Conserved Domains (3) summary

smart00185
Location:468 → 508

ARM; Armadillo/beta-catenin-like repeats

pfam00514
Location:511 → 552

Arm; Armadillo/beta-catenin-like repeat

sd00043
Location:439 → 464

ARM; armadillo repeat [structural motif]
XM_009301521.3 → XP_009299796.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X3

UniProtKB/TrEMBL

A0A8M3B2J5

Conserved Domains (3) summary

cd00020
Location:434 → 552

ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

pfam13646
Location:747 → 815

HEAT_2; HEAT repeats

sd00043
Location:439 → 464

ARM; armadillo repeat [structural motif]
XM_021476270.1 → XP_021331945.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X11

UniProtKB/TrEMBL

A0A8M9QE79

Conserved Domains (3) summary

smart00185
Location:468 → 508

ARM; Armadillo/beta-catenin-like repeats

pfam00514
Location:511 → 552

Arm; Armadillo/beta-catenin-like repeat

sd00043
Location:439 → 464

ARM; armadillo repeat [structural motif]
XM_009301520.3 → XP_009299795.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X1

UniProtKB/TrEMBL

A0A8M3ASI2

Conserved Domains (3) summary

cd00020
Location:434 → 552

ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

pfam13646
Location:757 → 825

HEAT_2; HEAT repeats

sd00043
Location:439 → 464

ARM; armadillo repeat [structural motif]
XM_009301523.3 → XP_009299798.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X5

UniProtKB/TrEMBL

A0A8M3ASE0

Conserved Domains (3) summary

cd00020
Location:434 → 552

ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

pfam13646
Location:757 → 825

HEAT_2; HEAT repeats

sd00043
Location:439 → 464

ARM; armadillo repeat [structural motif]
XM_021476273.1 → XP_021331948.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X15

UniProtKB/TrEMBL

A0A8M9PXY3

Conserved Domains (3) summary

smart00185
Location:386 → 426

ARM; Armadillo/beta-catenin-like repeats

sd00043
Location:357 → 382

ARM; armadillo repeat [structural motif]

cl27106
Location:357 → 470

PLN03200; cellulose synthase-interactive protein; Provisional
XM_021476272.1 → XP_021331947.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X13

UniProtKB/TrEMBL

A0A8M1NHH9, A2BGY1, F1QY26

Related

ENSDARP00000117208.2, ENSDART00000146070.4

Conserved Domains (3) summary

smart00185
Location:422 → 462

ARM; Armadillo/beta-catenin-like repeats

sd00043
Location:393 → 418

ARM; armadillo repeat [structural motif]

cl27106
Location:393 → 506

PLN03200; cellulose synthase-interactive protein; Provisional
XM_021476271.1 → XP_021331946.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X12

UniProtKB/TrEMBL

A0A8M9Q8X2

Conserved Domains (3) summary

smart00185
Location:422 → 462

ARM; Armadillo/beta-catenin-like repeats

sd00043
Location:393 → 418

ARM; armadillo repeat [structural motif]

cl27106
Location:393 → 506

PLN03200; cellulose synthase-interactive protein; Provisional
XM_021476269.1 → XP_021331944.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X10

UniProtKB/TrEMBL

A0A8M9Q3M5

Conserved Domains (3) summary

smart00185
Location:422 → 462

ARM; Armadillo/beta-catenin-like repeats

sd00043
Location:393 → 418

ARM; armadillo repeat [structural motif]

cl27106
Location:393 → 506

PLN03200; cellulose synthase-interactive protein; Provisional
XM_009301531.3 → XP_009299806.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X14

UniProtKB/TrEMBL

A0A8M3AZP7

Conserved Domains (3) summary

cd00020
Location:370 → 488

ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

pfam13646
Location:693 → 761

HEAT_2; HEAT repeats

sd00043
Location:375 → 400

ARM; armadillo repeat [structural motif]
XM_009301533.3 → XP_009299808.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X16

UniProtKB/TrEMBL

A0A8M3ASE4

Conserved Domains (3) summary

cd00020
Location:324 → 442

ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

pfam13646
Location:647 → 715

HEAT_2; HEAT repeats

sd00043
Location:329 → 354

ARM; armadillo repeat [structural motif]
XM_009301525.2 → XP_009299800.1 armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X6

UniProtKB/TrEMBL

A0A8M3B9P1

Conserved Domains (3) summary

cd00020
Location:434 → 552

ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

pfam13646
Location:757 → 825

HEAT_2; HEAT repeats

sd00043
Location:439 → 464

ARM; armadillo repeat [structural motif]