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    ZMYND11 zinc finger MYND-type containing 11 [ Homo sapiens (human) ]

    Gene ID: 10771, updated on 2-May-2024

    Summary

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    Official Symbol
    ZMYND11provided by HGNC
    Official Full Name
    zinc finger MYND-type containing 11provided by HGNC
    Primary source
    HGNC:HGNC:16966
    See related
    Ensembl:ENSG00000015171 MIM:608668; AllianceGenome:HGNC:16966
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BS69; BRAM1; MRD30
    Summary
    The protein encoded by this gene was first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
    Expression
    Ubiquitous expression in thyroid (RPKM 38.3), brain (RPKM 25.5) and 25 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    Location:
    10p15.3
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (130088..254637)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (122992..247610)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (176028..300577)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ReSE screen-validated silencer GRCh37_chr10:93160-93307 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2890 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2057 Neighboring gene tubulin beta 8 class VIII Neighboring gene IL9R pseudogene 2 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:180644-180822 Neighboring gene Sharpr-MPRA regulatory region 15592 Neighboring gene RNA, 5S ribosomal pseudogene 297 Neighboring gene DEAD-box helicase 20 pseudogene 1 Neighboring gene uncharacterized LOC107984190 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:294268-295467 Neighboring gene uncharacterized LOC107984191 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:310208-311407 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr10:315279-315788 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr10:315789-316297 Neighboring gene RNA, 5S ribosomal pseudogene 298 Neighboring gene disco interacting protein 2 homolog C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. ZMYND11 variants are a novel cause of centrotemporal and generalised epilepsies with neurodevelopmental disorder. Oates S, et al. Clin Genet, 2021 Oct. PMID 34216016
    2. ZMYND11-related syndromic intellectual disability: 16 patients delineating and expanding the phenotypic spectrum. Yates TM, et al. Hum Mutat, 2020 May. PMID 32097528
    3. The Transcriptional Repressor BS69 is a Conserved Target of the E1A Proteins from Several Human Adenovirus Species. Zhang A, et al. Viruses, 2018 Nov 22. PMID 30469473, Free PMC Article
    4. Phenotype comparison confirms ZMYND11 as a critical gene for 10p15.3 microdeletion syndrome. Tumiene B, et al. J Appl Genet, 2017 Nov. PMID 28933030
    5. A de novo missense mutation in ZMYND11 is associated with global developmental delay, seizures, and hypotonia. Moskowitz AM, et al. Cold Spring Harb Mol Case Stud, 2016 Sep. PMID 27626064, Free PMC Article

    See all (67) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MicroRNA-196b promotes cell growth and metastasis of ovarian cancer by targeting ZMYND11.
      Title: MicroRNA-196b promotes cell growth and metastasis of ovarian cancer by targeting ZMYND11.
    2. Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.
      Title: Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.
    3. ZMYND11 variants are a novel cause of centrotemporal and generalised epilepsies with neurodevelopmental disorder.
      Title: ZMYND11 variants are a novel cause of centrotemporal and generalised epilepsies with neurodevelopmental disorder.
    4. ZMYND11-related syndromic intellectual disability: 16 patients delineating and expanding the phenotypic spectrum.
      Title: ZMYND11-related syndromic intellectual disability: 16 patients delineating and expanding the phenotypic spectrum.
    5. ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism.
      Title: ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism.
    6. Our data indicate that increased association with BS69 restricts the function of type 2 EBNA2 as a transcriptional activator and driver of B cell growth and may contribute to reduced B-cell transformation by type 2 EBV.
      Title: Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity.
    7. the E1A proteins from HAdV-C5 and -A12 bind the cellular repressor protein BS69. This occurs via a SLiM containing a conserved PXLXP motif, which is present in CR2 of E1A. This SLiM confers interaction with the MYND domain of BS69.
      Title: The Transcriptional Repressor BS69 is a Conserved Target of the E1A Proteins from Several Human Adenovirus Species.
    8. The ZMYND11 gene has important functions in epigenetic regulation.
      Title: Phenotype comparison confirms ZMYND11 as a critical gene for 10p15.3 microdeletion syndrome.
    9. Taken together, ZMYND11 was demonstrated to be a potential and extremely promising suppressor of GBM, while miRNA-196a-5p was quite an important target of treatment of GBM.
      Title: Downregulation of ZMYND11 induced by miR-196a-5p promotes the progression and growth of GBM.
    10. Interaction with ZMYND11 mediates opposing roles of Ras-responsive ETS1 and ETS2.
      Title: Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2.
    Submit: New GeneRIF Correction See all GeneRIFs (26)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Intellectual disability, autosomal dominant 30
    MedGen: C4015167 OMIM: 616083 GeneReviews: Not available
    		Compare labs

    Copy number response

    Description
    Copy number response
    Triplosensitivity

    No evidence available (Last evaluated 2018-03-28)

    ClinGen Genome Curation PagePubMed
    Haploinsufficency

    Sufficient evidence for dosage pathogenicity (Last evaluated 2018-03-28)

    ClinGen Genome Curation PagePubMed

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC111056

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables methylated histone binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables methylated histone binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription corepressor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in defense response to virus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in negative regulation of JNK cascade IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of canonical NF-kappaB signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of extrinsic apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription elongation by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription elongation by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    zinc finger MYND domain-containing protein 11
    Names
    adenovirus 5 E1A-binding protein
    bone morphogenetic protein receptor-associated molecule 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029960.1 RefSeqGene

      Range
      5991..125173
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001202464.3 → NP_001189393.1  zinc finger MYND domain-containing protein 11 isoform c

      See identical proteins and their annotated locations for NP_001189393.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4), as well as variants 16-22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000385484.1, ENST00000403354.5
      Conserved Domains (3) summary
      cd05841
      Location:218 → 299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104 → 204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509 → 544
      zf-MYND; MYND finger

    2. NM_001202465.3 → NP_001189394.1  zinc finger MYND domain-containing protein 11 isoform d

      See identical proteins and their annotated locations for NP_001189394.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5), as well as variant 23, encodes isoform d.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS55697.1
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:187 → 268
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      pfam01753
      Location:478 → 513
      zf-MYND; MYND finger
      cl02556
      Location:95 → 173
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    3. NM_001202466.3 → NP_001189395.1  zinc finger MYND domain-containing protein 11 isoform e

      See identical proteins and their annotated locations for NP_001189395.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (6), as well as variant 24, encodes isoform e.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      UniProtKB/TrEMBL
      B7Z2J6, B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:217 → 298
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104 → 203
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:508 → 543
      zf-MYND; MYND finger

    4. NM_001202467.1 → NP_001189396.1  zinc finger MYND domain-containing protein 11 isoform f

      See identical proteins and their annotated locations for NP_001189396.1

      Status: REVIEWED

      Source sequence(s)
      AI244299, AL589988, BC034784, DB521520, DQ335454
      Consensus CDS
      CCDS91197.1
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000515849.1, ENST00000704335.1
      Conserved Domains (2) summary
      cd05841
      Location:218 → 299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104 → 204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...

    5. NM_001202468.1 → NP_001189397.1  zinc finger MYND domain-containing protein 11 isoform g

      See identical proteins and their annotated locations for NP_001189397.1

      Status: REVIEWED

      Source sequence(s)
      AI244299, AL589988, BC034784, DB521520, DQ335455
      Consensus CDS
      CCDS55696.1
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000452959.1, ENST00000558098.4
      Conserved Domains (3) summary
      cd05841
      Location:272 → 353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158 → 258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102 → 145
      PHD_BS69; PHD finger found in protein BS69

    6. NM_001330057.3 → NP_001316986.1  zinc finger MYND domain-containing protein 11 isoform h precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9), as well as variant 25, encodes isoform h.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (4) summary
      cd05841
      Location:255 → 336
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:141 → 241
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:85 → 128
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:546 → 581
      zf-MYND; MYND finger

    7. NM_001370097.3 → NP_001357026.1  zinc finger MYND domain-containing protein 11 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (10), as well as variants 1 and 11-15, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (4) summary
      cd05841
      Location:272 → 353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158 → 258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102 → 145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563 → 598
      zf-MYND; MYND finger

    8. NM_001370098.2 → NP_001357027.1  zinc finger MYND domain-containing protein 11 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11), as well as variants 1, 10, and 12-15, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (4) summary
      cd05841
      Location:272 → 353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158 → 258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102 → 145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563 → 598
      zf-MYND; MYND finger

    9. NM_001370099.2 → NP_001357028.1  zinc finger MYND domain-containing protein 11 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (12), as well as variants 1, 10, 11, and 13-15, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000371003.1, ENST00000381591.5
      Conserved Domains (4) summary
      cd05841
      Location:272 → 353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158 → 258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102 → 145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563 → 598
      zf-MYND; MYND finger

    10. NM_001370100.5 → NP_001357029.1  zinc finger MYND domain-containing protein 11 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (13), as well as variants 1, 10-12, 14, and 15, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000371017.6, ENST00000381604.9
      Conserved Domains (4) summary
      cd05841
      Location:272 → 353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158 → 258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102 → 145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563 → 598
      zf-MYND; MYND finger

    11. NM_001370101.2 → NP_001357030.1  zinc finger MYND domain-containing protein 11 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (14), as well as variants 1, 10-13, and 15, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (4) summary
      cd05841
      Location:272 → 353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158 → 258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102 → 145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563 → 598
      zf-MYND; MYND finger

    12. NM_001370102.2 → NP_001357031.1  zinc finger MYND domain-containing protein 11 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (15), as well as variants 1 and 10-14, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000515825.1, ENST00000704301.1
      Conserved Domains (4) summary
      cd05841
      Location:272 → 353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158 → 258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102 → 145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563 → 598
      zf-MYND; MYND finger

    13. NM_001370103.2 → NP_001357032.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (16), as well as variants 4 and 17-22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000515819.1, ENST00000704295.1
      Conserved Domains (3) summary
      cd05841
      Location:218 → 299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104 → 204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509 → 544
      zf-MYND; MYND finger

    14. NM_001370104.2 → NP_001357033.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (17), as well as variants 4, 16, and 18-22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:218 → 299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104 → 204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509 → 544
      zf-MYND; MYND finger

    15. NM_001370105.2 → NP_001357034.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (18), as well as variants 4, 16, 17, and 19-22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:218 → 299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104 → 204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509 → 544
      zf-MYND; MYND finger

    16. NM_001370106.2 → NP_001357035.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (19), as well as variants 4, 16-18, and 20-22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:218 → 299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104 → 204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509 → 544
      zf-MYND; MYND finger

    17. NM_001370107.2 → NP_001357036.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (20), as well as variants 4, 16-19, 21, and 22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:218 → 299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104 → 204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509 → 544
      zf-MYND; MYND finger

    18. NM_001370108.2 → NP_001357037.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (21), as well as variants 4, 16-20, and 22, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:218 → 299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104 → 204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509 → 544
      zf-MYND; MYND finger

    19. NM_001370109.2 → NP_001357038.1  zinc finger MYND domain-containing protein 11 isoform c

      Status: REVIEWED

      Description
      Transcript Variant: This variant (22), as well as variants 4 and 16-21, encodes isoform c.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS73060.1
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000515827.1, ENST00000704303.1
      Conserved Domains (3) summary
      cd05841
      Location:218 → 299
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104 → 204
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:509 → 544
      zf-MYND; MYND finger

    20. NM_001370110.2 → NP_001357039.1  zinc finger MYND domain-containing protein 11 isoform d

      Status: REVIEWED

      Description
      Transcript Variant: This variant (23), as well as variant 5, encodes isoform d.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS55697.1
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000473321.1, ENST00000602682.6
      Conserved Domains (3) summary
      cd05841
      Location:187 → 268
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      pfam01753
      Location:478 → 513
      zf-MYND; MYND finger
      cl02556
      Location:95 → 173
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    21. NM_001370111.2 → NP_001357040.1  zinc finger MYND domain-containing protein 11 isoform e

      Status: REVIEWED

      Description
      Transcript Variant: This variant (24), as well as variant 6, encodes isoform e.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      UniProtKB/TrEMBL
      B7Z2J6, B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:217 → 298
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:104 → 203
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:508 → 543
      zf-MYND; MYND finger

    22. NM_001370112.2 → NP_001357041.1  zinc finger MYND domain-containing protein 11 isoform h precursor

      Status: REVIEWED

      Description
      Transcript Variant: This variant (25), as well as variant 9, encodes isoform h.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (4) summary
      cd05841
      Location:255 → 336
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:141 → 241
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:85 → 128
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:546 → 581
      zf-MYND; MYND finger

    23. NM_001370113.2 → NP_001357042.1  zinc finger MYND domain-containing protein 11 isoform i

      Status: REVIEWED

      Description
      Transcript Variant: This variant (26), as well as variant 27, encodes isoform i.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS91196.1
      UniProtKB/TrEMBL
      B7Z3W2, E7ENI9
      Conserved Domains (3) summary
      cd05841
      Location:241 → 322
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      pfam01753
      Location:532 → 567
      zf-MYND; MYND finger
      cl02556
      Location:113 → 227
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    24. NM_001370114.2 → NP_001357043.1  zinc finger MYND domain-containing protein 11 isoform i

      Status: REVIEWED

      Description
      Transcript Variant: This variant (27), as well as variant 6, encodes isoform i.
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS91196.1
      UniProtKB/TrEMBL
      B7Z3W2, E7ENI9
      Related
      ENSP00000386010.1, ENST00000402736.5
      Conserved Domains (3) summary
      cd05841
      Location:241 → 322
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      pfam01753
      Location:532 → 567
      zf-MYND; MYND finger
      cl02556
      Location:113 → 227
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    25. NM_001370115.2 → NP_001357044.1  zinc finger MYND domain-containing protein 11 isoform j

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS91195.1
      UniProtKB/TrEMBL
      A0A0D9SGD6, B7Z3W2
      Related
      ENSP00000487386.2, ENST00000627286.2
      Conserved Domains (4) summary
      cd05841
      Location:271 → 352
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158 → 257
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102 → 145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:562 → 597
      zf-MYND; MYND finger

    26. NM_001370116.2 → NP_001357045.1  zinc finger MYND domain-containing protein 11 isoform k

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (4) summary
      cd05841
      Location:250 → 331
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:136 → 236
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:80 → 123
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:541 → 576
      zf-MYND; MYND finger

    27. NM_001370117.2 → NP_001357046.1  zinc finger MYND domain-containing protein 11 isoform l

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS91194.1
      UniProtKB/TrEMBL
      A0A994J6Y5, B7Z3W2
      Related
      ENSP00000515835.1, ENST00000704315.1
      Conserved Domains (4) summary
      cd05841
      Location:272 → 353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158 → 258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102 → 145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:540 → 575
      zf-MYND; MYND finger

    28. NM_001370118.2 → NP_001357047.1  zinc finger MYND domain-containing protein 11 isoform m

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922
      Consensus CDS
      CCDS91199.1
      UniProtKB/TrEMBL
      A0A994J4C0, B7Z3W2
      Related
      ENSP00000515854.1, ENST00000704343.1
      Conserved Domains (4) summary
      cd05841
      Location:232 → 313
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:118 → 218
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:62 → 105
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:523 → 558
      zf-MYND; MYND finger

    29. NM_001370119.2 → NP_001357048.1  zinc finger MYND domain-containing protein 11 isoform n

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      UniProtKB/TrEMBL
      A0A0A0MRY2
      Conserved Domains (4) summary
      cd05841
      Location:252 → 327
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158 → 252
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102 → 145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:514 → 549
      zf-MYND; MYND finger

    30. NM_001370120.2 → NP_001357049.1  zinc finger MYND domain-containing protein 11 isoform o

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922
      UniProtKB/TrEMBL
      B7Z3W2
      Conserved Domains (3) summary
      cd05841
      Location:196 → 277
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:82 → 182
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:487 → 522
      zf-MYND; MYND finger

    31. NM_001370121.2 → NP_001357050.1  zinc finger MYND domain-containing protein 11 isoform p

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922
      UniProtKB/TrEMBL
      B7Z3W2, Q5BJG6
      Conserved Domains (3) summary
      cd05841
      Location:178 → 259
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:64 → 164
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:469 → 504
      zf-MYND; MYND finger

    32. NM_001370122.2 → NP_001357051.1  zinc finger MYND domain-containing protein 11 isoform q

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS91198.1
      UniProtKB/TrEMBL
      A0A994J4I8, A0A994J4J2
      Related
      ENSP00000515831.1, ENST00000704307.1
      Conserved Domains (3) summary
      cd05841
      Location:170 → 251
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      pfam01753
      Location:461 → 496
      zf-MYND; MYND finger
      cl02556
      Location:104 → 149
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    33. NM_001370123.2 → NP_001357052.1  zinc finger MYND domain-containing protein 11 isoform r precursor

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      UniProtKB/TrEMBL
      A0A0A0MRY2, Q5UGI2
      Conserved Domains (3) summary
      cd05841
      Location:153 → 234
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      pfam01753
      Location:444 → 479
      zf-MYND; MYND finger
      cl02556
      Location:87 → 132
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.

    34. NM_001370124.3 → NP_001357053.1  zinc finger MYND domain-containing protein 11 isoform s

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922
      UniProtKB/TrEMBL
      B7Z3Z1
      Conserved Domains (3) summary
      cd05841
      Location:115 → 196
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:1 → 101
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      pfam01753
      Location:406 → 441
      zf-MYND; MYND finger

    35. NM_006624.7 → NP_006615.2  zinc finger MYND domain-containing protein 11 isoform a

      See identical proteins and their annotated locations for NP_006615.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1), as well as variants 10-15, encodes the longest isoform (a).
      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Consensus CDS
      CCDS7052.2
      UniProtKB/Swiss-Prot
      B2R6G8, B7Z293, F6UH50, Q15326, Q2LD45, Q2LD46, Q2LD47, Q2LD48, Q5VUI1, Q8N4B3
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000381053.3, ENST00000397962.8
      Conserved Domains (4) summary
      cd05841
      Location:272 → 353
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158 → 258
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102 → 145
      PHD_BS69; PHD finger found in protein BS69
      pfam01753
      Location:563 → 598
      zf-MYND; MYND finger

    36. NM_212479.4 → NP_997644.2  zinc finger MYND domain-containing protein 11 isoform b

      See identical proteins and their annotated locations for NP_997644.2

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL713922, AL731539
      Consensus CDS
      CCDS7053.2
      UniProtKB/TrEMBL
      B7Z3W2
      Related
      ENSP00000424205.2, ENST00000509513.6
      Conserved Domains (3) summary
      cd05841
      Location:271 → 352
      BS69_related; The PWWP domain is part of BS69 protein, a nuclear protein that specifically binds adenoviral E1A and Epstein-Barr viral EBNA2 proteins, suppressing their transactivation functions. BS69 is a multi-domain protein, containing bromo, PHD, PWWP, and MYND ...
      cd05492
      Location:158 → 257
      Bromo_ZMYND11; Bromodomain; ZMYND11_like sub-family. ZMYND11 or BS69 is a ubiquitously expressed nuclear protein that has been shown to associate with chromatin. It interacts with chromatin remodeling factors and might play a role in chromatin remodeling and gene ...
      cd15537
      Location:102 → 145
      PHD_BS69; PHD finger found in protein BS69

    RNA

    1. NR_163254.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AL589988, AL603831, AL713922, AL731539
      Related
      ENST00000381584.6

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      130088..254637
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017015594.2 → XP_016871083.1  zinc finger MYND domain-containing protein 11 isoform X1

      UniProtKB/TrEMBL
      B7Z3W2

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      122992..247610
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054364630.1 → XP_054220605.1  zinc finger MYND domain-containing protein 11 isoform X1

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q15326.2 GenPept UniProtKB/Swiss-Prot:Q15326

    Gene LinkOut

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