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    mps-2 MiRP K channel accessory Subunit [ Caenorhabditis elegans ]

    Gene ID: 173419, updated on 19-Jun-2024

    Summary

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    Gene symbol
    mps-2
    Gene description
    MiRP K channel accessory Subunit
    Locus tag
    CELE_K01A2.8
    See related
    AllianceGenome:WB:WBGene00019282
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables potassium channel regulator activity. Involved in regulation of chemotaxis and regulation of potassium ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including coelomocyte; enteric muscle; intestine; lateral ganglion; and rectal muscle. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See mps-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (309479..312157, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene AB hydrolase-1 domain-containing protein Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene DUF2231 domain-containing protein;Transmembrane protein Neighboring gene pseudo Neighboring gene MiRP K channel accessory Subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dual Role of an mps-2/KCNE-Dependent Pathway in Long-Term Memory and Age-Dependent Memory Decline. Fenyves BG, et al. Curr Biol, 2021 Feb 8. PMID 33259792
    2. An evolutionarily conserved family of accessory subunits of K+ channels. Cai SQ, et al. Cell Biochem Biophys, 2006. PMID 16943626
    3. A family of K+ channel ancillary subunits regulate taste sensitivity in Caenorhabditis elegans. Park KH, et al. J Biol Chem, 2005 Jun 10. PMID 15799965
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables potassium channel regulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in long-term memory IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of chemotaxis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of potassium ion transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of potassium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    MiRP K channel accessory Subunit
    NP_001033335.1
    • Product from WormBase gene class mps;
      Confirmed by transcript evidence
    NP_001379579.1
    • Product from WormBase gene class mps;
      Confirmed by transcript evidence
    NP_001379580.1
    • Product from WormBase gene class mps;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      309479..312157 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392992.1 → NP_001379580.1  MiRP K channel accessory Subunit [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86S20

    2. NM_001392991.1 → NP_001379579.1  MiRP K channel accessory Subunit [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q56VR8, Q9TZ55

    3. NM_001038246.6 → NP_001033335.1  MiRP K channel accessory Subunit [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001033335.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q56VR8, Q56VR9
    Nucleotide Protein
    Heading Accession and Version

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