Klra18 killer cell lectin-like receptor, subfamily A, member 18 [Mus musculus (house mouse)] - Gene

Summary

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Official Symbol: Klra18provided by MGI
Official Full Name: killer cell lectin-like receptor, subfamily A, member 18provided by MGI
Primary source: MGI:MGI:2136935
See related: AllianceGenome:MGI:2136935
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Ly49r
Summary: Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Annotation information: not in current annotation release
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Genomic context

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Location:: chromosome: 6

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data suggest Ly49:Ly49r interactions play critical role in influenza virus A host/pathogen interactions including immune evasion; knockout mice with natural killer cells lacking Ly49 survive influenza A infection; Ly49r restores susceptibility.
Title: Influenza Virus Targets Class I MHC-Educated NK Cells for Immunoevasion.

Submit: New GeneRIF Correction

General gene information

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Markers

NoName (e-PCR)
- UniSTS:488992

NoName (e-PCR)
- UniSTS:484912

NoName (e-PCR)
- UniSTS:494139

Klra4 (e-PCR), detects polymorphism
- UniSTS:143712

NoName (e-PCR)
- UniSTS:494960

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in plasma membrane	TAS Traceable Author Statement more info	PubMed

General protein information

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Preferred Names: killer cell lectin-like receptor, subfamily A, member 18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053153.2 → NP_444383.1 killer cell lectin-like receptor, subfamily A, member 18

See identical proteins and their annotated locations for NP_444383.1

Status: PROVISIONAL

Source sequence(s)

AF288377

UniProtKB/TrEMBL

Q2M2N3, Q4Z8P6, Q9JHV4

Conserved Domains (2) summary

cd03593
Location:143 → 256

CLECT_NK_receptors_like; C-type lectin-like domain (CTLD) of the type found in natural killer cell receptors (NKRs)

pfam08391
Location:40 → 154

Ly49; Ly49-like protein, N-terminal region