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    Y61A9LA.10 Bms1-type G domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178851, updated on 23-Nov-2023

    Summary

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    Gene symbol
    Y61A9LA.10
    Gene description
    Bms1-type G domain-containing protein
    Primary source
    WormBase:WBGene00022021
    Locus tag
    CELE_Y61A9LA.10
    See related
    AllianceGenome:WB:WBGene00022021
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable GTP binding activity; GTPase activity; and U3 snoRNA binding activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of 90S preribosome. Is expressed in head; nervous system; and pharynx. Human ortholog(s) of this gene implicated in nonsyndromic aplasia cutis congenita. Orthologous to human BMS1 (BMS1 ribosome biogenesis factor). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (4607039..4615817, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene ncRNA Neighboring gene transcellular chaperone signaling (x)cross tissue Neighboring gene DEK_C domain-containing protein Neighboring gene Protein sumv-2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables U3 snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Bms1-type G domain-containing protein
    NP_504245.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      4607039..4615817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071844.6 → NP_504245.3  Bms1-type G domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504245.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N306
      Conserved Domains (1) summary
      COG5192
      Location:10 → 1045
      BMS1; GTP-binding protein required for 40S ribosome biogenesis [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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