irf9 interferon regulatory factor 9 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: irf9provided by ZNC
Official Full Name: interferon regulatory factor 9provided by ZNC
Primary source: ZFIN:ZDB-GENE-040912-165
See related: Ensembl:ENSDARG00000016457 AllianceGenome:ZFIN:ZDB-GENE-040912-165
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ISGF3G; zgc:92097
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in immune system process and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in brain and kidney. Human ortholog(s) of this gene implicated in immunodeficiency 65. Orthologous to human IRF9 (interferon regulatory factor 9). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (13282709..13306886)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (13244441..13268585)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Much more significant induction of zebrafish IRF9 by zebrafish IFNgamma2.
Title: Expression regulation of zebrafish interferon regulatory factor 9 by promoter analysis.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables transcription cis-regulatory region binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in immune system process	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: interferon regulatory factor 9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205710.2 → NP_991273.2 interferon regulatory factor 9

See identical proteins and their annotated locations for NP_991273.2

Status: VALIDATED

Source sequence(s)

BX571950, EH433167, EH459171, EH462679, EH504444

UniProtKB/TrEMBL

A0A8M2B248, F1Q573

Related

ENSDARP00000123550.1, ENSDART00000137757.3

Conserved Domains (2) summary

pfam00605
Location:11 → 115

IRF; Interferon regulatory factor transcription factor

pfam10401
Location:216 → 398

IRF-3; Interferon-regulatory factor 3

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007123.7 Reference GRCz11 Primary Assembly

Range

13282709..13306886

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005156059.4 → XP_005156116.1 interferon regulatory factor 9 isoform X1

See identical proteins and their annotated locations for XP_005156116.1

UniProtKB/TrEMBL

A0A8M2B248, F1Q573

Conserved Domains (2) summary

pfam00605
Location:11 → 115

IRF; Interferon regulatory factor transcription factor

pfam10401
Location:216 → 398

IRF-3; Interferon-regulatory factor 3