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    cdc34b cell division cycle 34 homolog (S. cerevisiae) b [ Danio rerio (zebrafish) ]

    Gene ID: 436961, updated on 27-Mar-2024

    Summary

    Official Symbol
    cdc34bprovided by ZNC
    Official Full Name
    cell division cycle 34 homolog (S. cerevisiae) bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-439
    See related
    Ensembl:ENSDARG00000012627 AllianceGenome:ZFIN:ZDB-GENE-040718-439
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb34h09; fe17e09; zgc:91847; wu:fb34h09; wu:fe17e09
    Summary
    Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Is expressed in central nervous system. Orthologous to human CDC34 (cell division cycle 34, ubiqiutin conjugating enzyme). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See cdc34b in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (49007592..49031811, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (49273362..49297581, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101887100 Neighboring gene potassium inwardly rectifying channel subfamily J member 9 Neighboring gene abhydrolase domain containing 17A, depalmitoylase a Neighboring gene sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin conjugating enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    cell division cycle 34 homolog (S. cerevisiae) b
    Names
    ubiquitin-conjugating enzyme

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002688.1NP_001002688.1  cell division cycle 34 homolog (S. cerevisiae) b

      See identical proteins and their annotated locations for NP_001002688.1

      Status: PROVISIONAL

      Source sequence(s)
      BC076537
      UniProtKB/TrEMBL
      Q6DG18
      Related
      ENSDARP00000115088.1, ENSDART00000143471.2
      Conserved Domains (2) summary
      COG5078
      Location:9172
      COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
      cd00195
      Location:14172
      UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      49007592..49031811 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)