eef1a1b eukaryotic translation elongation factor 1 alpha 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: eef1a1bprovided by ZNC
Official Full Name: eukaryotic translation elongation factor 1 alpha 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050417-327
See related: Ensembl:ENSDARG00000069951 AllianceGenome:ZFIN:ZDB-GENE-050417-327
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: eef1a1; wu:fj34g08; zgc:110335
Summary: Predicted to enable GTP binding activity; GTPase activity; and translation elongation factor activity. Predicted to act upstream of or within translational elongation. Is expressed in brain; liver; muscle; and pleuroperitoneal region. Orthologous to several human genes including EEF1A1 (eukaryotic translation elongation factor 1 alpha 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (31112436..31130222)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (30308505..30326291)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables translation elongation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translational elongation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: elongation factor 1-alpha 1b

Names: eukaryotic translation elongation factor 1 alpha 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001017795.2 → NP_001017795.1 elongation factor 1-alpha 1b

See identical proteins and their annotated locations for NP_001017795.1

Status: VALIDATED

Source sequence(s)

BX901943

UniProtKB/TrEMBL

A0A8N7XJC3, A0A8N7XJC4, E7FD96, F1QI74, Q568F0

Related

ENSDARP00000069823.2, ENSDART00000075340.5

Conserved Domains (4) summary

PTZ00141
Location:1 → 460

PTZ00141; elongation factor 1- alpha; Provisional

cd01883
Location:9 → 238

EF1_alpha; Elongation Factor 1-alpha (EF1-alpha) protein family

cd03693
Location:242 → 332

EF1_alpha_II; Domain II of elongation factor 1-alpha

cd03705
Location:336 → 438

EF1_alpha_III; Domain III of Elongation Factor 1