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    map1aa microtubule-associated protein 1Aa [ Danio rerio (zebrafish) ]

    Gene ID: 100151220, updated on 27-Mar-2024

    Summary

    Official Symbol
    map1aaprovided by ZNC
    Official Full Name
    microtubule-associated protein 1Aaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-100426-2
    See related
    Ensembl:ENSDARG00000059601 AllianceGenome:ZFIN:ZDB-GENE-100426-2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7151905
    Summary
    Predicted to enable actin binding activity and microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization; neuron projection development; and regulation of microtubule depolymerization. Predicted to be part of microtubule associated complex. Predicted to be active in several cellular components, including dendrite; microtubule; and neuronal cell body. Is expressed in nervous system; neural tube; and trigeminal placode. Orthologous to human MAP1A (microtubule associated protein 1A). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See map1aa in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (52830325..52876657, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (52555254..52601585, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene mitochondrial methionyl-tRNA formyltransferase Neighboring gene diphosphoinositol pentakisphosphate kinase 1a Neighboring gene uncharacterized LOC108190716 Neighboring gene tumor protein p53 binding protein, 1 Neighboring gene tubulin gamma complex component 4 Neighboring gene CDKN2A interacting protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in axonogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in dendrite development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of microtubule depolymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    part_of microtubule associated complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    microtubule-associated protein 1A; microtubule-associated protein 1B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      52830325..52876657 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001921037.7XP_001921072.3  microtubule-associated protein 1A isoform X1

      See identical proteins and their annotated locations for XP_001921072.3

      UniProtKB/TrEMBL
      A0A8M1QUZ1
      Conserved Domains (1) summary
      cl23716
      Location:232283
      metallo-hydrolase-like_MBL-fold; mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain
    2. XM_005166530.4XP_005166587.1  microtubule-associated protein 1A isoform X1

      See identical proteins and their annotated locations for XP_005166587.1

      UniProtKB/TrEMBL
      A0A8M1QUZ1
      Related
      ENSDARP00000142517.2, ENSDART00000172910.3
      Conserved Domains (1) summary
      cl23716
      Location:232283
      metallo-hydrolase-like_MBL-fold; mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain
    3. XM_009303461.3XP_009301736.1  microtubule-associated protein 1A isoform X2

      UniProtKB/TrEMBL
      A0A140LH51, A0A8M3B1H0, F1QIM1
      Related
      ENSDARP00000142581.2, ENSDART00000172951.3
      Conserved Domains (1) summary
      cl23716
      Location:50101
      metallo-hydrolase-like_MBL-fold; mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain