cox6b1 cytochrome c oxidase subunit 6B1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cox6b1provided by ZNC
Official Full Name: cytochrome c oxidase subunit 6B1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-448
See related: Ensembl:ENSDARG00000045230 AllianceGenome:ZFIN:ZDB-GENE-040718-448
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fa92g05; zgc:92631; wu:fa92g05; si:dkey-161j23.2
Summary: Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrion. Is expressed in several structures, including gill; heart; liver; pronephros; and skeletal muscle. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human COX6B1 (cytochrome c oxidase subunit 6B1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 24

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (39606051..39610578, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (39718204..39722731, complement)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex IV	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytochrome c oxidase subunit 6B1

Names: cytochrome c oxidase subunit VIb polypeptide 1

NP_001002695.1

EC 7.1.1.9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002695.3 → NP_001002695.1 cytochrome c oxidase subunit 6B1

See identical proteins and their annotated locations for NP_001002695.1

Status: VALIDATED

Source sequence(s)

EH487817, EH583430

UniProtKB/TrEMBL

A0A8M1N0X5, Q6DH63

Related

ENSDARP00000066505.4, ENSDART00000066506.5

Conserved Domains (1) summary

cd00926
Location:8 → 85

Cyt_c_Oxidase_VIb; Cytochrome c oxidase subunit VIb. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of ...