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    tsp-8 Tetraspanin [ Caenorhabditis elegans ]

    Gene ID: 181567, updated on 11-Apr-2024

    Summary

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    Gene symbol
    tsp-8
    Gene description
    Tetraspanin
    Primary source
    WormBase:WBGene00006634
    Locus tag
    CELE_F33C8.3
    See related
    AllianceGenome:WB:WBGene00006634
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in body wall musculature. Orthologous to human TSPAN4 (tetraspanin 4) and TSPAN9 (tetraspanin 9). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See tsp-8 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (14726626..14729503, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene CUB domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DUF38 domain-containing protein Neighboring gene KIF-binding protein Neighboring gene MFS domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Tetraspanin
    NP_510445.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      14726626..14729503 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078044.7 → NP_510445.1  Tetraspanin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510445.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19983
      Conserved Domains (3) summary
      cd03127
      Location:108 → 243
      tetraspanin_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
      pfam00335
      Location:8 → 276
      Tetraspannin; Tetraspanin family
      cl00275
      Location:13 → 108
      Heme_Cu_Oxidase_I; Heme-copper oxidase subunit I. Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane. The superfamily is ...
    Nucleotide Protein
    Heading Accession and Version

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