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    hint-3 Adenosine 5'-monophosphoramidase HINT3 [ Caenorhabditis elegans ]

    Gene ID: 182943, updated on 12-Jun-2024

    Summary

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    Gene symbol
    hint-3
    Gene description
    Adenosine 5'-monophosphoramidase HINT3
    Locus tag
    CELE_C26F1.7
    See related
    AllianceGenome:WB:WBGene00016150
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human HINT3 (histidine triad nucleotide binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See hint-3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (7760474..7761633)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Glycosyltransferase family 92 protein Neighboring gene pseudo Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene Ground-like domain-containing protein Neighboring gene Large ribosomal subunit protein eL39

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Adenosine 5'-monophosphoramidase HINT3
    NP_001256089.1
    • Confirmed by transcript evidence
    NP_001256090.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      7760474..7761633
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001269160.3 → NP_001256089.1  Adenosine 5'-monophosphoramidase HINT3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256089.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3KFR7
      Conserved Domains (1) summary
      cd01278
      Location:35 → 141
      aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...

    2. NM_001269161.2 → NP_001256090.1  Adenosine 5'-monophosphoramidase HINT3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256090.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18227
      Conserved Domains (1) summary
      cd01278
      Location:10 → 116
      aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
    Nucleotide Protein
    Heading Accession and Version

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