U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Ighv4-2 immunoglobulin heavy variable V4-2 [ Mus musculus (house mouse) ]

    Gene ID: 668423, updated on 1-Apr-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Ighv4-2provided by MGI
    Official Full Name
    immunoglobulin heavy variable V4-2provided by MGI
    Primary source
    MGI:MGI:5009840
    See related
    IMGT/GENE-DB:IGHV4-2; AllianceGenome:MGI:5009840
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Igh; IGH@
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    12 F1; 12 62.26 cM
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (113976764..113977059, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (114013144..114013439, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene immunoglobulin heavy chain complex Neighboring gene immunoglobulin heavy variable 11-1 Neighboring gene immunoglobulin heavy variable 14-2 Neighboring gene immunoglobulin heavy variable V11-2 Neighboring gene immunoglobulin heavy variable 3-2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Natural polyreactive immunoglobulin A antibodies produced in mouse Peyer's patches. Shimoda M, et al. Immunology, 1999 May. PMID 10447709, Free PMC Article
    2. A single VH-gene associated with a variety of D- and J-segments encodes for a large family of ABPC48-related antibodies induced by antiidiotypic immunization. Legrain P, et al. Mol Immunol, 1985 Apr. PMID 3929072
    3. V kappa gene usage, idiotype expression, and antigen binding among clones expressing the VHX24 gene family derived from naive and anti-idiotype immune BALB/c mice. Bonilla FA, et al. J Immunol, 1990 Jul 15. PMID 2114445
    4. Age-related changes in antigen-specific natural antibodies are influenced by sex. Webster SE, et al. Front Immunol, 2022. PMID 36713434, Free PMC Article
    5. Characterization of gene use and efficacy of mouse monoclonal antibodies to Streptococcus pneumoniae serotype 8. Yano M, et al. Clin Vaccine Immunol, 2011 Jan. PMID 21068211, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Other Names

    • Ig heavy chain V-region
    • IgA heavy chain VDJ region
    • IgM heavy chain VDJ region
    • IgM heavy chain variable region
    • anti-Epstein-Barr virus gp42 immunoglobulin heavy chain variable region
    • anti-SARS-CoV-2 spike protein immunoglobulin heavy chain variable region
    • anti-meningococcal polysaccharide group C monoclonal antibody 2010.10 immunoglobulin heavy chain
    • immunoglobulin active Ab3 heavy chain variable region
    • immunoglobulin gamma 1 heavy chain variable region
    • immunoglobulin gamma 2b heavy chain variable region
    • immunoglobulin gamma 3 heavy chain variable region
    • immunoglobulin heavy chain variable region
    • immunoglobulin mu heavy chain variable region
    • monoclonal anti-alpha-1,3-galactosyltransferase IgM heavy chain VDJ region
    • natural polyreactive IgA antibody

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_005838.1 

      Range
      765548..765843 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      113976764..113977059 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.