aoc1 amine oxidase copper containing 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: aoc1provided by ZNC
Official Full Name: amine oxidase copper containing 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-061103-112
See related: Ensembl:ENSDARG00000061355 AllianceGenome:ZFIN:ZDB-GENE-061103-112
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: abp1; zgc:154101; si:ch211-286c5.2
Summary: Predicted to enable copper ion binding activity; diamine oxidase activity; and primary amine oxidase activity. Predicted to be involved in amine metabolic process and response to antibiotic. Predicted to be active in plasma membrane. Is expressed in ventral habenular nucleus. Orthologous to human AOC1 (amine oxidase copper containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 24

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	24	NC_007135.7 (40001290..40009419, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	24	NC_007135.6 (40113443..40121572, complement)

Chromosome 24 - NC_007135.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables D-lysine oxidase activity	IEA Inferred from Electronic Annotation more info
enables copper ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables copper ion binding	IEA Inferred from Electronic Annotation more info
enables diamine oxidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	IEA Inferred from Electronic Annotation more info
enables primary amine oxidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables primary amine oxidase activity	IEA Inferred from Electronic Annotation more info
enables quinone binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in amine metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within amine metabolic process	IEA Inferred from Electronic Annotation more info
involved_in response to antibiotic	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: amiloride-sensitive amine oxidase [copper-containing]

Names: amiloride binding protein 1 (amine oxidase (copper-containing)); dao; diamine oxidase; histaminase

NP_001071066.1

EC 1.4.3.6

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077598.1 → NP_001071066.1 amiloride-sensitive amine oxidase [copper-containing] precursor

See identical proteins and their annotated locations for NP_001071066.1

Status: PROVISIONAL

Source sequence(s)

BC125956

UniProtKB/TrEMBL

A0A8N7UYD6, A0JMP5

Related

ENSDARP00000081856.4, ENSDART00000087422.5

Conserved Domains (3) summary

pfam01179
Location:290 → 702

Cu_amine_oxid; Copper amine oxidase, enzyme domain

pfam02727
Location:35 → 124

Cu_amine_oxidN2; Copper amine oxidase, N2 domain

pfam02728
Location:140 → 239

Cu_amine_oxidN3; Copper amine oxidase, N3 domain