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    Tulp2 TUB like protein 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361576, updated on 3-Apr-2024

    Summary

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    Official Symbol
    Tulp2provided by RGD
    Official Full Name
    TUB like protein 2provided by RGD
    Primary source
    RGD:1310551
    See related
    Ensembl:ENSRNOG00000020927 AllianceGenome:RGD:1310551
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in protein localization to cilium. Predicted to be located in extracellular region. Predicted to be active in cilium. Orthologous to human TULP2 (TUB like protein 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 913.5) See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tulp2 in Genome Data Viewer
    Location:
    1q22
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (105098884..105136243)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (95962496..95999775)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (101474334..101511621)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene ferritin light chain 1 Neighboring gene BCL2 associated X, apoptosis regulator Neighboring gene dihydrodiol dehydrogenase Neighboring gene nucleobindin 1 Neighboring gene protein phosphatase 1, regulatory subunit 15A Neighboring gene pleckstrin homology domain containing A4 Neighboring gene transfer RNA serine (anticodon AGA) 17

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. Mukhopadhyay S, et al. Genes Dev, 2010 Oct 1. PMID 20889716, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in protein localization to cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tubby-related protein 2
    Names
    tubby-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012168.1 → NP_001012168.1  tubby-related protein 2

      See identical proteins and their annotated locations for NP_001012168.1

      Status: PROVISIONAL

      Source sequence(s)
      BC084696
      UniProtKB/TrEMBL
      A0A8I6G891, Q5XFX6
      Related
      ENSRNOP00000062682.2, ENSRNOT00000064245.3
      Conserved Domains (2) summary
      pfam01167
      Location:232 → 479
      Tub; Tub family
      pfam16322
      Location:13 → 167
      Tub_N; Tubby N-terminal

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      105098884..105136243
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063266801.1 → XP_063122871.1  tubby-related protein 2 isoform X8

    2. XM_006229103.5 → XP_006229165.2  tubby-related protein 2 isoform X2

      UniProtKB/TrEMBL
      A6JB47
      Related
      ENSRNOP00000072107.2

    3. XM_063266742.1 → XP_063122812.1  tubby-related protein 2 isoform X1

    4. XM_063266753.1 → XP_063122823.1  tubby-related protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A0G2K250

    5. XM_063266764.1 → XP_063122834.1  tubby-related protein 2 isoform X4

    6. XM_063266786.1 → XP_063122856.1  tubby-related protein 2 isoform X6

    7. XM_006229106.4 → XP_006229168.1  tubby-related protein 2 isoform X7

      UniProtKB/TrEMBL
      A6JB47
      Conserved Domains (2) summary
      pfam01167
      Location:252 → 499
      Tub; Tub family
      pfam16322
      Location:1 → 187
      Tub_N; Tubby N-terminal

    8. XM_017589366.3 → XP_017444855.1  tubby-related protein 2 isoform X9

      UniProtKB/TrEMBL
      A0A8I6G891
      Conserved Domains (2) summary
      pfam01167
      Location:196 → 443
      Tub; Tub family
      pfam16322
      Location:5 → 131
      Tub_N; Tubby N-terminal

    9. XM_063266775.1 → XP_063122845.1  tubby-related protein 2 isoform X5

    10. XM_008759398.4 → XP_008757620.1  tubby-related protein 2 isoform X9

      See identical proteins and their annotated locations for XP_008757620.1

      UniProtKB/TrEMBL
      A0A8I6G891
      Related
      ENSRNOP00000082997.1
      Conserved Domains (2) summary
      pfam01167
      Location:196 → 443
      Tub; Tub family
      pfam16322
      Location:5 → 131
      Tub_N; Tubby N-terminal

    11. XM_063266811.1 → XP_063122881.1  tubby-related protein 2 isoform X10

    Nucleotide Protein Strain
    Heading Accession and Version

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