Btg4 BTG anti-proliferation factor 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Btg4provided by RGD
Official Full Name: BTG anti-proliferation factor 4provided by RGD
Primary source: RGD:1308809
See related: Ensembl:ENSRNOG00000011277 AllianceGenome:RGD:1308809
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: SCIR-27
Summary: Predicted to be involved in negative regulation of cell population proliferation and negative regulation of mitotic cell cycle. Predicted to be active in cytoplasm and nucleus. Orthologous to human BTG4 (BTG anti-proliferation factor 4). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Testes (RPKM 7.2), Lung (RPKM 2.2) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 8q23

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (60307090..60322167)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (51410774..51425802)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	8	NC_005107.4 (55408917..55508100)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

BE119988 (e-PCR)
- UniSTS:249321

RH127262 (e-PCR)
- UniSTS:208378

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables mRNA 3'-UTR binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within maternal-to-zygotic transition of gene expression	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of cell population proliferation	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within negative regulation of mitotic cell cycle	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: protein BTG4

Names: B-cell translocation gene 4; BTG family member 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.